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[用于牛、猪和羊的磷酸酯制剂及其对胆碱酯酶活性的影响。3. 磷酸酯制剂在猪中的应用及其对乙酰胆碱酯酶活性的影响]

[Phosphoric acid ester preparations used in cattle, swine and sheep with special reference to cholinesterase activity. 3. Use of phosphoric acid ester preparations and their effect on acetylcholinesterase activity in swine].

作者信息

Mieth K, Beier D, Losch K

出版信息

Arch Exp Veterinarmed. 1975;29(4):491-500.

PMID:1190970
Abstract

The use of organophosphorus preparations in the treatment of ectoparasites and endoparasites of pigs is discussed. Treatment of 43 store pigs with preparations produced in the German Democratic Republic by washing and by the pour-on method resulted in considerable inactivation of acetylcholinesterase, which implies good systemic action. Overdosage increased this effect, but without producing signs of toxicity. The oral dosages for pigs cited in the literature were confirmed. Repeated treatment was recommended for the best results, as pigs rapidly break down the preparations. It is necessary to take into account adverse effects of oral administration on palatability of the ration and on weight gain. Addition of a preparation to a batch of food for a group of pigs is likely to be less successful than individual dosing, which is the best method for sows.

摘要

本文讨论了有机磷制剂在治疗猪体外寄生虫和体内寄生虫方面的应用。用德意志民主共和国生产的制剂通过冲洗和浇泼法对43头育肥猪进行治疗,结果显示乙酰胆碱酯酶有相当程度的失活,这表明该制剂有良好的全身作用。过量用药会增强这种效果,但未产生毒性迹象。文献中引用的猪口服剂量得到了证实。由于猪会迅速分解这些制剂,因此建议重复治疗以获得最佳效果。有必要考虑口服给药对日粮适口性和体重增加的不利影响。将制剂添加到一组猪的一批食物中可能不如个体给药成功,个体给药是母猪的最佳方法。

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