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Alteplase for stroke: money and optimistic claims buttress the "brain attack" campaign.

作者信息

Lenzer Jeanne

机构信息

Oak Ridge Journalism, Ellenville, NY 12428, USA.

出版信息

BMJ. 2002 Mar 23;324(7339):723-9. doi: 10.1136/bmj.324.7339.723.

DOI:10.1136/bmj.324.7339.723
PMID:11909792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1122648/
Abstract
摘要

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Why don't more patients receive intravenous rt-PA for acute stroke?为什么更多的急性中风患者没有接受静脉注射重组组织型纤溶酶原激活剂（rt-PA）治疗？
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Thrombolysis for acute ischaemic stroke.急性缺血性卒中的溶栓治疗
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Pharmaceutical sponsorship bias influences thrombolytic literature in acute ischemic stroke.制药公司赞助会影响急性缺血性脑卒中溶栓文献。
West J Emerg Med. 2011 Nov;12(4):435-41. doi: 10.5811/westjem.2011.5.2166.
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Concerned Journals, Editors And ICMJE.相关期刊、编辑和国际医学期刊编辑委员会
Mens Sana Monogr. 2007 Jan;5(1):90-107. doi: 10.4103/0973-1229.32152.
10
Foundations and task forces.基金会与特别工作组。
Mens Sana Monogr. 2007 Jan;5(1):79-89. doi: 10.4103/0973-1229.32151.

本文引用的文献

1
Evidence of publication bias in reporting acute stroke clinical trials.急性中风临床试验报告中发表偏倚的证据。
Neurology. 2006 Sep 26;67(6):973-9. doi: 10.1212/01.wnl.0000237331.16541.ac.
2
Relationships between authors of clinical practice guidelines and the pharmaceutical industry.临床实践指南作者与制药行业之间的关系。
JAMA. 2002 Feb 6;287(5):612-7. doi: 10.1001/jama.287.5.612.
3
ATLANTIS trial: results for patients treated within 3 hours of stroke onset. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke.亚特兰蒂斯试验：卒中发作3小时内接受治疗患者的结果。急性缺血性卒中阿替普酶溶栓非介入治疗
Stroke. 2002 Feb;33(2):493-5. doi: 10.1161/hs0202.102599.
4
Number needed to treat (NNT): estimation of a measure of clinical benefit.需治疗人数（NNT）：临床获益衡量指标的估计值。
Stat Med. 2001 Dec 30;20(24):3947-62. doi: 10.1002/sim.1173.
5
Improving delivery of acute stroke therapy: The TLL Temple Foundation Stroke Project.改善急性中风治疗的提供：TLL 坦普尔基金会中风项目。
Stroke. 2002 Jan;33(1):160-6. doi: 10.1161/hs0102.101990.
6
Extending tissue plasminogen activator use to community and rural stroke patients.将组织纤溶酶原激活剂的应用扩展至社区及农村中风患者。
Stroke. 2002 Jan;33(1):141-6. doi: 10.1161/hs0102.100481.
7
Industry-sponsored clinical research: a double-edged sword.行业资助的临床研究：一把双刃剑。
Lancet. 2001 Dec 1;358(9296):1893-5. doi: 10.1016/S0140-6736(01)06891-X.
8
Annals supplement on the American Heart Association proceedings.《美国心脏协会会议纪要》增刊
Ann Emerg Med. 2001 Nov;38(5):605. doi: 10.1067/mem.2001.119276.
9
Sponsorship, authorship, and accountability.赞助、作者身份与责任。
Lancet. 2001 Sep 15;358(9285):854-6. doi: 10.1016/s0140-6736(01)06035-4.
10
Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study.早期卒中治疗与更好的预后相关：美国国立神经疾病与卒中研究所rt-PA卒中研究
Neurology. 2000 Dec 12;55(11):1649-55. doi: 10.1212/wnl.55.11.1649.