Hamdi M, Ben Amor H, Ben Chaabane T, Kchelfi S, Nouisri L, Khelil A
Service d'Orthopédie-Traumatologie, Hôpital Militaire Principal d'Instruction de Tunis, Tunisie.
Acta Orthop Belg. 2002 Feb;68(1):87-92.
Multicentric giant cell tumors of bone are rare; they represent less than 1% of all giant cell tumors. We report the case of a 35-year-old right-handed man, who presented in 1985 with a giant cell tumor of the upper end of the right humerus. After failure of conservative treatment (curettage and bone grafting), resection-arthrodesis of the shoulder with a free vascularized fibular autograft was performed. Three years later, the patient developed an osteolytic lesion of the lower end of the ipsilateral radius, involving the soft tissues and the wrist joint. He was treated with resection-arthrodesis of the wrist with a free vascularized fibular graft. The histologic study confirmed the diagnosis of giant cell tumor of similar grade. After 13 years follow-up, the patient had a satisfactory function of the limb and no recurrence of the tumor was noted.
骨的多中心巨细胞瘤很罕见,占所有巨细胞瘤的比例不到1%。我们报告一例35岁右利手男性病例,该患者于1985年出现右肱骨上端巨细胞瘤。保守治疗(刮除术和骨移植)失败后,采用带血管蒂游离腓骨自体移植进行肩关节切除关节融合术。三年后,患者同侧桡骨下端出现溶骨性病变,累及软组织和腕关节。采用带血管蒂游离腓骨移植进行腕关节切除关节融合术对其进行治疗。组织学研究证实为相同分级的巨细胞瘤。经过13年的随访,患者肢体功能良好,未发现肿瘤复发。