Narang U
Closure Medical Corporation, Raleigh, North Carolina, USA.
Compend Contin Educ Dent Suppl. 2001(32):7-11; quiz 22.
Cyanoacrylate, a synthetic adhesive, is a fast polymerizable liquid monomer. Serendipity led to the discovery of cyanoacrylate adhesives in 1951. Today, a specific cyanoacrylate monomer, 2-octyl cyanoacrylate, is being used in a topical medical adhesive formulation. The only over-the-counter cyanoacrylate-based product cleared by the Food and Drug Administration is Colgate ORABASE Soothe.N. Seal Liquid Protectant. Upon application, this liquid monomer formulation polymerizes instantly into a thin, flexible polymer film that adheres tenaciously to mucosal tissue. This polymer film creates a mechanical barrier that provides immediate and long-term pain relief of oral ulcerations and irritations, and maintains a natural healing environment for the area to heal.
氰基丙烯酸酯是一种合成粘合剂，是一种可快速聚合的液态单体。1951年偶然发现了氰基丙烯酸酯粘合剂。如今，一种特定的氰基丙烯酸酯单体，即2-辛基氰基丙烯酸酯，正被用于一种局部医用粘合剂配方中。美国食品药品监督管理局批准的唯一一种非处方氰基丙烯酸酯类产品是高露洁ORABASE舒缓密封液体保护剂。使用时，这种液态单体配方会立即聚合成一层薄而柔韧的聚合物薄膜，该薄膜会牢固地粘附在粘膜组织上。这种聚合物薄膜形成了一种机械屏障，可为口腔溃疡和刺激提供即时和长期的疼痛缓解，并为该区域的愈合维持自然的愈合环境。
