硅藻中的一种新型磺基脂质。

A novel sulfonolipid in diatoms.

作者信息

Anderson R, Livermore B P, Volcani B E, Kates M

出版信息

Biochim Biophys Acta. 1975 Nov 21;409(2):259-63. doi: 10.1016/0005-2760(75)90160-5.

PMID:1191667

Abstract

A new sulfonolipid has been isolated from a non-photosynthetic diatom, Nitzschia alba, by thin-layer and column chromatography on silicic acid, and characterized by 35S-labeling, mobility on thin-layer chromatography, infrared and NMR spectroscopy and products of hydrolysis, as a ceramide sulfonic acid (N-acyl sphingosine-1-sulfonic acid). The long-chain base moiety was shown by identification of the products of periodate or periodate-permanganate oxidation to consist of a C18-trans-sphingosine backbone linked directly by a C-S linkage through C1 to a SO3 group. The N-acyl groups were mainly isoheptadecanoic (64%) and palmitic (26%) acids.

摘要

通过在硅酸上进行薄层色谱和柱色谱，从一种非光合硅藻——白菱形藻（Nitzschia alba）中分离出一种新的磺基脂质，并通过35S标记、薄层色谱迁移率、红外光谱和核磁共振光谱以及水解产物对其进行表征，确定其为神经酰胺磺酸（N-酰基鞘氨醇-1-磺酸）。通过对高碘酸盐或高碘酸盐-高锰酸盐氧化产物的鉴定表明，长链碱基部分由一个C18反式鞘氨醇主链组成，该主链通过C1的C-S键直接与一个SO3基团相连。N-酰基主要是异十七烷酸（64%）和棕榈酸（26%）。