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贫血会增加孕期吸烟对胎儿造成的风险吗?

Does anaemia increase the risks to the fetus caused by smoking in pregnancy?

作者信息

Dow T G, Rooney P J, Spence M

出版信息

Br Med J. 1975 Nov 1;4(5991):253-4. doi: 10.1136/bmj.4.5991.253.

Abstract

A significantly greater rise in carboxyhaemoglobin concentration in response to smoking a single cigarette was shown in pregnant (3-9% increase) as opposed to non-pregnant (2-1% increase) women. This was more pronounced when anaemia was present (5-0% increase) and appeared to be inversely related to the haemoglobin concentration. We suggest that the risks to the fetus may be particularly increased when anaemia complicates pregnancy in women who smoke cigarettes.

摘要

与非孕妇(升高2-1%)相比,孕妇吸一支烟后碳氧血红蛋白浓度显著升高(升高3-9%)。当存在贫血时,这种情况更明显(升高5-0%),且似乎与血红蛋白浓度呈负相关。我们认为,对于吸烟且贫血并发妊娠的女性,其胎儿面临的风险可能会特别增加。

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本文引用的文献

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Carbon monoxide-induced arterial hypoxemia.一氧化碳所致动脉低氧血症。
Science. 1969 Jun 13;164(3885):1297-8. doi: 10.1126/science.164.3885.1297.
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Smoking in pregnancy and subsequent child development.孕期吸烟与儿童后续发育
Br Med J. 1973 Dec 8;4(5892):573-5. doi: 10.1136/bmj.4.5892.573.
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Smoking during pregnancy and its effects on the fetus.
J Obstet Gynaecol Br Commonw. 1972 Sep;79(9):782-7. doi: 10.1111/j.1471-0528.1972.tb12920.x.
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Comparison of increases in carboxyhaemoglobin after smoking "extra-mild" and "non-mild" cigarettes.
Lancet. 1973 Sep 29;2(7831):687-90. doi: 10.1016/s0140-6736(73)92533-6.
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Cigarette smoking and exposure to carbon monoxide.吸烟与接触一氧化碳。
Ann N Y Acad Sci. 1970 Oct 5;174(1):135-47. doi: 10.1111/j.1749-6632.1970.tb49780.x.
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Anaemia of pregnancy: the changing postwar pattern.妊娠贫血:战后模式的变化
Br Med J. 1975 Feb 1;1(5952):259-61. doi: 10.1136/bmj.1.5952.259.

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