Maghur H A, Ben-Musa A A, Salim M E, Abuzakhar S S
Mesallata Cardiothoracic Centre, Libya.
Pediatr Cardiol. 2002 Jan-Feb;23(1):49-52. doi: 10.1007/s00246-001-0012-4. Epub 2002 Feb 19.
Since 1992 we have performed the modified Blalock-Taussig shunt (MBTS) for cyanotic children in Libya. This retrospective study reviews our results as a developing country, comparing them with those in the literature, and makes suggestions to improve our results. Between May 1992 and May 1998, 94 children (58 males and 36 females) underwent 100 MBTSs in Mesallata Cardiothoracic Centre, Libya. The age ranged from 4 days to 15 years, (median 12 months) and 25 patients were neonates. Patients' weights ranged from 3 to 31 kg (median 6.4 kg). Eighty-nine shunts were performed on the left side and 11 on the right. A 6-mm polytetrafluoroethylene graft was used in 68 children and a 4-mm graft in 32 cases. Tetralogy of Fallot (TOF) comprised the majority of cases (63; 67%), the remaining 31 (33%) included tricuspid atresia (13), pulmonary atresia (9), univentricular heart complex (6), and others (3). Acute shunt failure occurred in 3 cases (2 with 4-mm and 1 with 6-mm grafts), all of which had not received perioperative heparin. Hospital mortality was 6% (6 patients); risk factors were neonates, a diagnosis other than TOF, and emergency surgery. There were 12 late deaths, 6 of which were due to sepsis. Follow-up was achieved in 82 of 88 early survivors for a period of 2 to 60 months (median 26 months). All surviving patients had subjective and objective improvement. We conclude that MBTS is an excellent palliative procedure for children requiring a systemic-pulmonary shunt in developing as well as developed countries. This series shows an early mortality rate comparable to that of other studies, but the late mortality is higher, mainly due to sepsis, which warrants further attention.
自1992年以来,我们在利比亚为患有紫绀型心脏病的儿童实施了改良布莱洛克 - 陶西格分流术(MBTS)。这项回顾性研究审视了我们作为一个发展中国家所取得的结果,将其与文献中的结果进行比较,并提出改进结果的建议。1992年5月至1998年5月期间,94名儿童(58名男性和36名女性)在利比亚梅萨拉塔心胸中心接受了100次MBTS手术。年龄范围为4天至15岁(中位数为12个月),25名患者为新生儿。患者体重范围为3至31千克(中位数为6.4千克)。89次分流手术在左侧进行,11次在右侧进行。68名儿童使用了6毫米的聚四氟乙烯移植物,32例使用了4毫米的移植物。法洛四联症(TOF)占大多数病例(63例;67%),其余31例(33%)包括三尖瓣闭锁(13例)、肺动脉闭锁(9例)、单心室心脏复合体(6例)及其他(3例)。3例发生急性分流失败(2例使用4毫米移植物,1例使用6毫米移植物),所有这些病例均未在围手术期接受肝素治疗。医院死亡率为6%(6例患者);危险因素为新生儿、非TOF诊断以及急诊手术。有12例晚期死亡,其中6例死于败血症。88名早期幸存者中有82名获得随访,随访期为2至60个月(中位数为26个月)。所有存活患者在主观和客观方面均有改善。我们得出结论,对于发展中国家和发达国家中需要体肺分流术的儿童,MBTS是一种出色的姑息性手术。本系列显示早期死亡率与其他研究相当,但晚期死亡率较高,主要原因是败血症,这值得进一步关注。