Lam G K, Henkelman R M, Harrison R W, Skarsgard L D, Palcic B
Phys Med Biol. 1979 Nov;24(6):1243-9. doi: 10.1088/0031-9155/24/6/014.
A simple, flexible technique has been developed to generate uniform depth dose profiles for the biomedical pion beam at TRIUMF using dynamic momentum control and linear programming. Either the entrance dose or the irradiation time required for a certain dose over the uniform region can be minimised. The dynamic momentum control can operate automatically under computer control even with a highly unstable beam. Cell survival profiles have been obtained for this uniform dose distribution using the gelatin technique. The RBE increases with increasing depth through the uniform dose region.
已经开发出一种简单、灵活的技术，利用动态动量控制和线性规划为 TRIUMF 的生物医学π介子束生成均匀的深度剂量分布。可以将均匀区域内的入射剂量或达到特定剂量所需的照射时间降至最低。即使在光束高度不稳定的情况下，动态动量控制也能在计算机控制下自动运行。使用明胶技术已经获得了这种均匀剂量分布的细胞存活曲线。在均匀剂量区域内，相对生物效应随着深度的增加而增加。
