拉斯穆森脑炎：自身免疫性细胞毒性T淋巴细胞的作用
Rasmussen's encephalitis: a role for autoimmune cytotoxic T lymphocytes.
作者信息
Bauer Jan, Bien Christian G, Lassmann Hans
机构信息
Brain Research Institute, Division of Neuroimmunology, University of Vienna, Vienna, Austria.
出版信息
Curr Opin Neurol. 2002 Apr;15(2):197-200. doi: 10.1097/00019052-200204000-00012.
Abstract
The present review describes advances in Rasmussen's encephalitis (also known as Rasmussen's syndrome), an unihemispheric intractable epileptic disease with persistent inflammation. Specific attention is given to the recent recognition of cytotoxicity by CD8+/granzyme-B-positive T lymphocytes as a new pathogenic mechanism of neuronal damage.
摘要
本综述描述了拉斯穆森脑炎（也称为拉斯穆森综合征）的研究进展，这是一种伴有持续性炎症的单侧半球难治性癫痫疾病。特别关注的是，最近认识到CD8+/颗粒酶B阳性T淋巴细胞的细胞毒性是神经元损伤的一种新的致病机制。
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