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[汞与阿尔茨海默病之间的关系?]

[Relation between mercury and Alzheimer's disease?].

作者信息

Schuurs A H, de Wolff F A

机构信息

Vakgroep Cariologie en Endodontologie, Academisch Centrum Tandheelkunde Amsterdam (ACTA), Louwesweg 1, 1066 EA Amsterdam.

出版信息

Ned Tijdschr Tandheelkd. 1997 Jun;104(6):219-22.

Abstract

Mercury from dental silver amalgam has been suggested to be linked with Alzheimer's disease. The percentage in the population (formerly) possessing amalgam restorations exceeds that of Alzheimer patients. Therefore, low levels of mercury in the brain are unlikely to cause the disease. However, studies indicating increased levels of mercury in Alzheimer brains compared to controls have been criticised. In contrast, it has been proven that an inherited trait accounts for a minor proportion of Alzheimer's patients. Moreover, education--or related psychosocial factors--instead of amalgam has been found to be associated with the disease. Therefore, it does not seem warranted as yet to conclude that mercury is an etiological factor in Alzheimer's disease.

摘要

牙科银汞合金中的汞被认为与阿尔茨海默病有关。(以前)拥有汞合金修复体的人群比例超过了阿尔茨海默病患者的比例。因此,大脑中低水平的汞不太可能导致这种疾病。然而,与对照组相比,阿尔茨海默病患者大脑中汞含量增加的研究受到了批评。相比之下,已经证明遗传特征在阿尔茨海默病患者中占比很小。此外,人们发现与该疾病相关的是教育——或相关的社会心理因素——而非汞合金。因此,目前似乎尚无理由得出汞是阿尔茨海默病病因的结论。

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