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[巴马科肺结核的影像学和细菌学数据与HIV状态的关系]

[Radiographic and bacteriologic data on pulmonary tuberculosis in Bamako as a function of HIV status].

作者信息

Kayantao D, Maïga I, Bougoudogo F, Pouabé Tchameni R, Kéïta B, Sangaré S

出版信息

Rev Pneumol Clin. 2001 Dec;57(6):423-6.

Abstract

This prospective study included patients treated for tuberculosis between January 998 and April 1999 in the pneumology unit of the Point G Hospital in Bamako. The purpose was to analyze chest x-ray and bacteriological findings in HIV+ and HIV- patients. All patients had clinical and radiographic signs suggestive of tuberculosis with one or several sputum samples and HIV serology. Among the 127 patients, 36 were HIV positive (28.3%). There was no sex predominance in the HIV+ patients (p = 0.3). The most common radiographic aspect associated nodules and infiltration irrespective of the immune status (p = 0.014). Characteristic features of the chest x-rays in HIV-positive patients were: frequent military forms and rare cavernous forms (p = 0.007). Sputum tests were positive more often in HIV-negative than HIV-positive patients (p = 0.0003). The diagnosis of tuberculosis was retained in 11.7% of the patients with negative microbiology despite repeated samples. A normal chest x-ray was observed solely in one HIV-negative patient.

摘要

这项前瞻性研究纳入了1998年1月至1999年4月在巴马科G点医院肺病科接受结核病治疗的患者。目的是分析HIV阳性和HIV阴性患者的胸部X光和细菌学检查结果。所有患者均有临床和影像学表现提示结核病,并进行了一份或多份痰标本检查及HIV血清学检测。在127例患者中,36例HIV阳性(28.3%)。HIV阳性患者中无性别优势(p = 0.3)。无论免疫状态如何,最常见的影像学表现为结节和浸润(p = 0.014)。HIV阳性患者胸部X光的特征为:粟粒型常见,空洞型少见(p = 0.007)。痰检HIV阴性患者阳性率高于HIV阳性患者(p = 0.0003)。尽管多次取样,仍有11.7%微生物学检查阴性的患者被确诊为结核病。仅1例HIV阴性患者胸部X光正常。

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