Diotallevi P, Cristofaro M, Natale L, Scano M, Geraci S, Montella F, Serra G
Azienda Ospedaliera San Giovanni, Addolorata.
Radiol Med. 1998 Jul-Aug;96(1-2):55-61.
We compared two groups of risk patients to try to identify different radiologic patterns in pulmonary tuberculosis.
74 subjects, divided into two groups (HIV+:27; HIV-:47) were included since 1993. The patients were examined with chest X-ray (CXR) and CT.
In the HIV+ group we observed 40 radiologic alterations, with 6 cases of bilateral lung involvement and 9 of atypical localizations; particularly: 11 consolidations, 8 cavitations, 5 miliary diseases, 9 hilar or mediastinal adenopathies, 3 extrapulmonary localizations and 4 negative CXRs. In the HIV- group we found 53 radiologic alterations, with 6 cases of bilateral lung involvement and 3 of atypical localizations; particularly: 12 consolidations, 25 cavitations, 5 nodular patterns, 1 miliary disease, 5 nodal disease, 4 pleural diseases and 1 negative CRX.
In HIV- patients lung consolidations and tysiogen patterns are significantly prevalent, while miliary diseases, mediastinal diseases and atypical localizations and negative CRXs are more frequent in HIV+ patients. We found miliary diseases, mediastinal diseases and extrapulmonary localizations also in HIV- patients with heavily impaired social, economic and sanitary conditions. This alterations indicate compromised host resistance, independent of the causes and modalities of immunodeficiency. The distinction between primary and secondary tuberculosis is currently not mandatory.
我们比较了两组风险患者,试图识别肺结核不同的放射学模式。
自1993年起纳入74名受试者,分为两组(HIV阳性:27例;HIV阴性:47例)。对患者进行胸部X线(CXR)和CT检查。
在HIV阳性组中,我们观察到40例放射学改变,其中6例双侧肺部受累,9例为非典型定位;具体如下:11例实变,8例空洞形成,5例粟粒性病变,9例肺门或纵隔淋巴结肿大,3例肺外定位,4例CXR阴性。在HIV阴性组中,我们发现53例放射学改变,其中6例双侧肺部受累,3例为非典型定位;具体如下:12例实变,25例空洞形成,5例结节样改变,1例粟粒性病变,5例淋巴结病变,4例胸膜疾病,1例CRX阴性。
在HIV阴性患者中,肺部实变和干酪样模式显著多见,而粟粒性病变、纵隔疾病、非典型定位和CXR阴性在HIV阳性患者中更为常见。我们在社会、经济和卫生条件严重受损的HIV阴性患者中也发现了粟粒性病变、纵隔疾病和肺外定位。这些改变表明宿主抵抗力受损,与免疫缺陷的原因和方式无关。目前区分原发性和继发性肺结核并非必要。