Kneas Knsti A, Demas J N, Nguyen Bryant, Lockhart Aaron, Xu Wenying, DeGraff B A
Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319, USA.
Anal Chem. 2002 Mar 1;74(5):1111-8. doi: 10.1021/ac010867v.
To ascertain the relationship between the physical properties of polymer supports and the observed response of luminescence-based oxygen sensors, a quenching-based method was developed to measure oxygen diffusion in polymers. The method offers advantages over existing quenching-based techniques since it allows a simple correction for films of high optical density, and the computations do not assume uniform oxygen concentration throughout the film. Diffusion coefficients (D) were measured for a series of sensors with [Ru(Ph2phen)3]Cl2 (Ph2phen = 4,7-diphenyl-1,10-phenanthroline) asthe luminophore and polystyrene, poly(trimethylsilylmethyl methacrylate), poly(butyl methacrylate), poly(trimethylsilylmethyl methacrylate-co-butyl methacrylate), or poly(trimethylsilylmethyl methacrylate-co-1H, 1H-heptafluorobutyl methacrylate) as the support. The solvent from which the films were cast was varied, and filler materials such as hydrophobic, amorphous silica or tributyl phosphate plasticizer were added. Results are interpreted by a domain model in which the local environment of the sensor, rather than the bulk properties of the polymer, is the most critical parameter in sensor design.
为了确定聚合物载体的物理性质与基于发光的氧传感器所观察到的响应之间的关系，开发了一种基于猝灭的方法来测量聚合物中的氧扩散。该方法相对于现有的基于猝灭的技术具有优势，因为它允许对高光密度的薄膜进行简单校正，并且计算不假定整个薄膜中的氧浓度均匀。测量了一系列以[Ru(Ph2phen)3]Cl2（Ph2phen = 4,7-二苯基-1,10-菲咯啉）为发光体，以聚苯乙烯、聚（三甲基硅基甲基丙烯酸甲酯）、聚（甲基丙烯酸丁酯）、聚（三甲基硅基甲基丙烯酸甲酯-共-甲基丙烯酸丁酯）或聚（三甲基硅基甲基丙烯酸甲酯-共-1H,1H-七氟丁基甲基丙烯酸甲酯）为载体的传感器的扩散系数（D）。改变了浇铸薄膜所用的溶剂，并添加了诸如疏水性无定形二氧化硅或磷酸三丁酯增塑剂等填充材料。结果通过一个区域模型来解释，在该模型中，传感器的局部环境而非聚合物的整体性质是传感器设计中最关键的参数。
