Aniansson Gustaf, Svensson Henry, Becker Magnus, Ingvarsson Leif
Department of Plastic and Reconstructive Surgery, Malmö University Hospital, SE 205 02 Malmö, Sweden.
Scand J Plast Reconstr Surg Hand Surg. 2002;36(1):9-15. doi: 10.1080/028443102753478318.
The purpose of the present study was to analyse the incidence of acute and secretory otitis media (OM), and feeding with breast milk, and the use of a grommet in children with a cleft palate (CP/CLP) or cleft lip (CL), compared with controls. A total of 84 children between 6 and 10 years of age were studied. The CP/CLP group consisted of 48 children with an isolated cleft palate (n = 28), or a cleft lip and palate (n = 20). The CL group consisted of 15 children with an isolated cleft lip. The controls were 21 children without clefts. Children with CP/CLP had acute OM significantly more often than children without clefts (43/48 compared with 10/21), and secretory OM (40/48 compared with 4/21), despite the use of grommets. CP/CLP children were breast fed for a mean of 2.8 months (range 0-13), compared with 3.6 months (0-12) for CL, and 7.5 (0-24) months for controls. There was a significant correlation during the first 18 months of life between longer duration of feeding with breast milk and a lower incidence of acute and secretory OM in the three study groups combined. The incidence of otitis media was not affected by care in a day centre, having a sibling attending a day care centre, or by the family's medical history. Despite cleft repair and early treatment with grommets, both secretory and acute OM are common among children with cleft palate, presumably as a result of their eustachian tube dysfunction. The present study suggests that premature cessation of feeding with breast milk may contribute to an increased incidence of acute and secretory OM.
本研究的目的是分析腭裂(CP/CLP)或唇裂(CL)患儿与对照组相比,急性和分泌性中耳炎(OM)的发病率、母乳喂养情况以及鼓膜切开置管术的使用情况。共研究了84名6至10岁的儿童。CP/CLP组由48名患儿组成,其中孤立性腭裂患儿28名,唇腭裂患儿20名。CL组由15名单纯唇裂患儿组成。对照组为21名无腭裂的儿童。尽管使用了鼓膜切开置管术,但CP/CLP患儿发生急性中耳炎的频率明显高于无腭裂患儿(43/48对比10/21),分泌性中耳炎的发生率也更高(40/48对比4/21)。CP/CLP患儿的母乳喂养平均时长为2.8个月(范围0至13个月),CL患儿为3.6个月(0至12个月),对照组为7.5个月(0至24个月)。在三个研究组合并分析中,出生后前18个月内母乳喂养时间越长,急性和分泌性中耳炎的发病率越低,二者存在显著相关性。日托中心照料、有兄弟姐妹在日托中心以及家族病史均不影响中耳炎的发病率。尽管进行了腭裂修复并早期实施了鼓膜切开置管术,但分泌性和急性中耳炎在腭裂患儿中仍很常见,这可能是由于他们的咽鼓管功能障碍所致。本研究表明,过早停止母乳喂养可能会导致急性和分泌性中耳炎的发病率增加。