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具有不同亚型特征的皮肤恶性纤维组织细胞瘤

Cutaneous malignant fibrous histiocytoma with the characteristics of different variants.

作者信息

Kakizoe Eiichi, Kakizoe Fukuko, Kakizoe Kenji, Okunishi Hideki

机构信息

Kakizoe Clinic of Dermatology, Kurume, Japan.

出版信息

Cutis. 2002 Mar;69(3):211-4.

Abstract

We report the case of a 50-year-old woman with cutaneous malignant fibrous histiocytoma (MFH) on the right hypogastric region. A purplish-red blood-filled tumor, approximately 40 mm in diameter, was detected on the region. A histopathologic analysis of the excised tumor showed that it extended from the upper dermis to the subcutaneous tissue over the fascia and, furthermore, that a variety of cells, from highly atypical spindle shaped to histiocytelike, were embedded in the collagenous stroma without forming a capsule. The storiform pattern was not significant. In addition, an area occupied primarily by multinucleated giant cells and rich in vascular components was observed in the deep portion of the tumor that came into contact with the bloody contents. Based on these findings, the patient was diagnosed as having a cutaneous MFH exhibiting the characteristics of different variants.

摘要

我们报告了一例50岁女性患者,其右下腹区域患有皮肤恶性纤维组织细胞瘤(MFH)。在该区域检测到一个直径约40mm的紫红色充血性肿瘤。对切除肿瘤的组织病理学分析显示,肿瘤从真皮上层延伸至筋膜上方的皮下组织,此外,多种细胞,从高度非典型的梭形细胞到组织细胞样细胞,嵌入胶原性基质中,未形成包膜。席纹状模式不明显。此外,在与血性内容物接触的肿瘤深部观察到一个主要由多核巨细胞占据且血管成分丰富的区域。基于这些发现,该患者被诊断为具有不同变体特征的皮肤MFH。

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