Roberts Christine L, Raynes-Greenow Camille H, Algert Charles S, Peat Brian
New South Wales Centre for Perinatal Health Services Research, Department of Obstetrics and Gynecology, University of Sydney, Australia.
Aust N Z J Obstet Gynaecol. 2002 Feb;42(1):51-4. doi: 10.1111/j.0004-8666.2002.00057.x.
To examine higher order multiple pregnancy and birth rates in NSW, and to describe trends in the characteristics and management of these births.
Cross-sectional analytic study.
New South Wales, Australia.
Two hundred and ninety-one women who gave birth to triplets, quadruplets or quintuplets (880 babies) from 1 January 1990 to 31 December 1999.
Data were obtained from the NSW Midwives Data Collection and rates over time were calculated.
Higher order multiple birth and pregnancy rates (> or = 20 weeks), place of birth, mode of delivery, fetal death rates and Apgar scores.
There was no significant change in the number or rate of higher order multiple births in NSW during the 1990s with an average annual rate of 10.3/10,000 births or 3.5/10,000 pregnancies > or = 20 weeks. Among women with higher order multiple pregnancies, those aged > or = 35 years increased from 19% in 1990 to 47% in 1999. There was also a trend towards delivery in a perinatal centre from 56% to 70%, and vaginal birth from 18% to 28%. There were no significant changes in infant outcomes.
The increases in higher order multiple pregnancies observed in Australia in the 1980s, and into the 1990s in other countries, have not persisted in NSW, suggesting that guidelines for limiting the number of embryos/oocytes transferred in assisted reproductive technologies have been widely adopted.
研究新南威尔士州高阶多胎妊娠及出生率,并描述这些分娩的特征及管理趋势。
横断面分析研究。
澳大利亚新南威尔士州。
1990年1月1日至1999年12月31日期间分娩三胞胎、四胞胎或五胞胎的291名妇女(880名婴儿)。
数据取自新南威尔士州助产士数据收集,计算不同时间段的发生率。
高阶多胎分娩及妊娠率(≥20周)、出生地、分娩方式、胎儿死亡率及阿氏评分。
20世纪90年代新南威尔士州高阶多胎分娩的数量及发生率无显著变化,平均年发生率为10.3/10000例分娩或3.5/10000例≥20周妊娠。在高阶多胎妊娠妇女中,年龄≥35岁者从1990年的19%增至1999年的47%;在围产中心分娩的比例也呈上升趋势,从56%升至70%,阴道分娩比例从18%升至28%;婴儿结局无显著变化。
澳大利亚在20世纪80年代出现的高阶多胎妊娠增加情况,以及其他国家在20世纪90年代出现的类似情况,在新南威尔士州并未持续,这表明辅助生殖技术中限制移植胚胎/卵母细胞数量的指南已被广泛采用。