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钙对慢性肾衰竭甲状旁腺功能亢进的直接影响。

The direct effect of calcium on the hyperparathyroidism of chronic renal failure.

作者信息

Kaye M

出版信息

Clin Sci Mol Med. 1975 Nov;49(5):481-4. doi: 10.1042/cs0490481.

DOI:10.1042/cs0490481
PMID:1192706
Abstract
  1. The direct effect of calcium on the hyperparathyroidism of chronic renal failure was studied in rats with induced chronic renal failure, who were fed on a diet low in phosphate and who received supplemental phosphate by injection. They were given a normal (0-8%), or (0-1%) or high (1-7%) calcium diet. 2. The animals on the low calcium diet had larger parathyroids and more severe bone disease at the end of 4 weeks, indicating the importance of calcium intake in directly influencing the degree of hyperparathyroidism. 3. Increasing the calcium content of the diet from 0-8% to 1-7% produced no additional benefits.
摘要
  1. 在诱导产生慢性肾衰竭的大鼠中研究了钙对慢性肾衰竭甲状旁腺功能亢进的直接影响。这些大鼠食用低磷饮食,并通过注射补充磷。它们被给予正常(0.8%)、低(0.1%)或高(1.7%)钙饮食。2. 低钙饮食的动物在4周结束时甲状旁腺更大,骨病更严重,这表明钙摄入量在直接影响甲状旁腺功能亢进程度方面的重要性。3. 将饮食中的钙含量从0.8%提高到1.7%没有带来额外益处。

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