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对苯丙胺处理大鼠刻板运动活动的旷场研究。

An open field study of stereotyped locomotor activity in amphetamine-treated rats.

作者信息

Schiørring E

出版信息

Psychopharmacology (Berl). 1979;66(3):281-7. doi: 10.1007/BF00428320.

DOI:10.1007/BF00428320
PMID:119275
Abstract

It is said that amphetamine induces stereotypy and locomotion in rats; however, the present paper shows amphetamine-induced stereotyped locomotion by analyzing the route of locomotion in an open field. Details of the analysis are given, normal as well as stereotypic features are discerned, and the results are discussed in relation to contemporary views on locomotion and exploration and on the mechanisms of amphetamine effect.

摘要

据说苯丙胺能诱发大鼠的刻板行为和活动；然而，本文通过分析旷场中的活动路径展示了苯丙胺诱发的刻板运动。给出了分析细节，辨别了正常特征和刻板特征，并结合当代关于运动和探索以及苯丙胺作用机制的观点对结果进行了讨论。

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An open field study of stereotyped locomotor activity in amphetamine-treated rats.对苯丙胺处理大鼠刻板运动活动的旷场研究。
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Time course of amphetamine-induced locomotor stereotypy in an open field.苯丙胺诱导的旷场活动刻板行为的时间进程。
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Atypical neuroleptics clozapine and thioridazine enhance amphetamine-induced stereotypy.非典型抗精神病药物氯氮平和硫利达嗪会增强苯丙胺诱导的刻板行为。
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本文引用的文献

1
Manipulatory motivation in the infant rhesus monkey.恒河猴幼崽的操控动机。
J Comp Physiol Psychol. 1956 Oct;49(5):444-8. doi: 10.1037/h0047817.
2
Response by the rat to environmental change.大鼠对环境变化的反应。
J Comp Physiol Psychol. 1956 Feb;49(1):93-5. doi: 10.1037/h0045411.
3
Stimulus context and satiation.刺激情境与饱腹感。
一氧化氮相关化合物在精神分裂症急性氯胺酮动物模型中的作用。
BMC Neurosci. 2015 Mar 7;16:9. doi: 10.1186/s12868-015-0149-3.
4
Long-term effects of cocaine experience on neuroplasticity in the nucleus accumbens core of addiction-prone rats.可卡因经历对易成瘾大鼠伏隔核核心区神经可塑性的长期影响。
Neuroscience. 2013 Sep 17;248:571-84. doi: 10.1016/j.neuroscience.2013.06.042. Epub 2013 Jun 28.
5
A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men.精神疾病中功能失调性探索行为的逆向转化研究：从小鼠到人类
Arch Gen Psychiatry. 2009 Oct;66(10):1072-80. doi: 10.1001/archgenpsychiatry.2009.58.
6
A novel method for automatic quantification of psychostimulant-evoked route-tracing stereotypy: application to Mus musculus.一种自动量化精神兴奋剂诱发的路径追踪刻板行为的新方法：应用于小家鼠。
Psychopharmacology (Berl). 2008 Mar;196(4):591-602. doi: 10.1007/s00213-007-0994-6. Epub 2007 Dec 21.
7
Behavioral effects of orally administered glycine in socially housed monkeys chronically treated with phencyclidine.
Psychopharmacology (Berl). 2007 May;192(1):27-38. doi: 10.1007/s00213-007-0771-6. Epub 2007 Mar 29.
8
Atypical antipsychotics, clozapine and sulpiride do not antagonise amphetamine-induced stereotyped locomotion.非典型抗精神病药物氯氮平和舒必利不会拮抗苯丙胺引起的刻板运动。
Psychopharmacology (Berl). 1994 Feb;114(1):123-30. doi: 10.1007/BF02245453.
9
The effects of radio-frequency lesions of the nucleus accumbens on d-amphetamine-induced locomotor and rearing behavior in rats.
Psychopharmacology (Berl). 1981;75(4):363-7. doi: 10.1007/BF00435854.
10
Depletion of brain serotonin by 5,7-dihydroxytryptamine alters the response to amphetamine and the habituation of locomotor activity in rats.5,7-二羟基色胺使大鼠脑内血清素耗竭，会改变大鼠对苯丙胺的反应以及运动活动的习惯化。
Psychopharmacology (Berl). 1985;87(4):400-5. doi: 10.1007/BF00432502.
J Comp Physiol Psychol. 1956 Feb;49(1):90-2. doi: 10.1037/h0040984.
4
Behavioural effects in rats of morphine and amphetamine and of a combination of the two drugs.吗啡、安非他命及二者组合对大鼠行为的影响。
Psychopharmacologia. 1970;16(4):305-12. doi: 10.1007/BF00404736.
5
Behavioural and pharmacological studies on morphine-induced excitation of rats. Possible relation to brain catecholamines.吗啡诱发大鼠兴奋的行为学和药理学研究。与脑内儿茶酚胺的可能关系。
Psychopharmacologia. 1973;29(4):317-28. doi: 10.1007/BF00429279.
6
Methylphenidate induced inhibition of exploratory behaviour in rats.哌醋甲酯诱导大鼠探索行为受到抑制。
Life Sci I. 1972 Feb 15;11(4):161-7. doi: 10.1016/0024-3205(72)90257-3.
7
The role of social isolation and sex in determining effects of chlordiazepoxide and methylphenidate on exploratory behaviour.
Psychopharmacologia. 1972;27(4):359-66. doi: 10.1007/BF00429389.
8
Evolving behavior in the clinical and experimental amphetamine (model) psychosis.
Am J Psychiatry. 1973 Oct;130(10):1088-93. doi: 10.1176/ajp.130.10.1088.