Feliciotti F, Campagnacci R, Perretta S, Paganini A M, Guerrieri M, Tamburini A, De Sanctis A, Lezoche E
Department of General Surgery, University of Ancona, "Umberto I" Hospital, Largo Cappelli 1, 60121 Ancona, Italy.
Surg Endosc. 2002 Mar;16(3):539. doi: 10.1007/s00464-001-4177-y. Epub 2001 Dec 17.
Juxtaglomerular cell tumor is an extremely rare neoplasm of the kidney that causes blood hypertension. A 45-year-old man with persistent hypertension was referred to our department because of a solid mass of unclear origin (kidney? colon?) located in the right mesorenal region that had been detected by Computed tomography (CT) scan, ultrasonography, and colonoscopy. Serum levels of renin, plasma renin activity (PRA), and aldosterone were all normal. Operatively, four 10/12-mm ports were placed, ultrasonography confirmed a well-encapsulated lesion of the kidney. Ultrasonic shears and cautery were used to resect the lesion, including 5 mm of free renal tissue. Postoperatively, a prompt normalization of blood pressure was observed. The pathological findings showed a juxtaglomerular cell tumor. The definitive diagnosis of juxtaglomerular cell tumor is made on the basis of laboratory findings, and imaging studies, Its definitive treatment is surgical excision which can be accomplished successfully with minimally invasive surgery.
球旁细胞瘤是一种极其罕见的可导致高血压的肾脏肿瘤。一名45岁患有持续性高血压的男性因计算机断层扫描（CT）、超声检查和结肠镜检查发现右肾周区域有一个起源不明的实性肿块（肾脏？结肠？）而被转诊至我科。肾素、血浆肾素活性（PRA）和醛固酮的血清水平均正常。手术时，置入了四个10/12毫米的端口，超声检查确认了一个包膜完整的肾脏病变。使用超声刀和电灼切除病变，包括5毫米的游离肾组织。术后，血压迅速恢复正常。病理检查结果显示为球旁细胞瘤。球旁细胞瘤的确诊基于实验室检查结果和影像学研究，其明确的治疗方法是手术切除，微创手术可成功完成。
