Mauguiere F, Blanc A, Piccinali J P, Courjon J
Rev Electroencephalogr Neurophysiol Clin. 1979 Apr-Jun;9(2):149-55. doi: 10.1016/s0370-4475(79)80069-6.
Clinically evident epileptic seizures were observed in 145 patients during the first week of traumatic coma. They frequently occurred during the first day in young subjects in reactive coma, and were often isolated attacks. When ssen at a later stage they are more common in adults with non-reactive coma. The partial or generalised nature of the seizures, the depth of the coma, and the chronological order in which the seizures appear have no bearing on the etiology; the only positive finding was that recurrent seizures were more frequent in patients with intracranial hematoma (18,6% of the patients). The early appearance of seizures does not worsen the prognosis of reactive coma or non-reactive coma in young people. Critical discharges without clinical manifestations were present in 37 patients with traumatic coma during the first week. The average age of these injured patients was higher, and the prognosis for non-reactive coma worse in this group. The comatous state does not modify the clinical aspects or the etiological significance of these early post-traumatic discharges.
在创伤性昏迷的第一周，145例患者出现了临床明显的癫痫发作。在反应性昏迷的年轻受试者中，癫痫发作常在第一天频繁发生，且多为孤立发作。在后期出现时，癫痫发作在无反应性昏迷的成人中更为常见。癫痫发作的部分性或全身性、昏迷深度以及癫痫发作出现的时间顺序与病因无关；唯一的阳性发现是颅内血肿患者的复发癫痫发作更为频繁（占患者的18.6%）。癫痫发作的早期出现并不会使年轻人反应性昏迷或无反应性昏迷的预后恶化。在创伤性昏迷的第一周，37例患者出现了无临床表现的临界放电。这些受伤患者的平均年龄较高，该组无反应性昏迷的预后较差。昏迷状态不会改变这些创伤后早期放电的临床特征或病因学意义。
