通过基于聚合酶链反应的分子检测法诊断的一名危重症儿科患者的白色念珠菌性心内膜炎。
Candida albicans endocarditis diagnosed by PCR-based molecular assay in a critically ill pediatric patient.
作者信息
Posteraro Brunella, Valentini Piero, Delogu Angelica, De Rosa Gabriella, Boccacci Simona, Sanguinetti Maurizio, Nacci Aldo, Sopo Stefano Miceli, Ranno Orazio, Morace Giulia, Fadda Giovanni
机构信息
Institutes of Microbiology, Catholic University of the Sacred Heart, Rome, Italy.
出版信息
Scand J Infect Dis. 2002;34(2):145-7. doi: 10.1080/00365540110077173.
A young Down's syndrome patient developed tricuspid valve endocarditis several years after undergoing surgical closure of a congenital ventricular septal defect. Fungal etiology was established by PCR amplification of the Candida albicans ERG11 gene. Although antifungal therapy was administered, surgical replacement of the infected valve was required to eliminate the infection.
一名唐氏综合征青年患者在先天性室间隔缺损手术闭合数年之后发生了三尖瓣心内膜炎。通过对白色念珠菌ERG11基因进行PCR扩增确定了真菌病因。尽管给予了抗真菌治疗，但仍需要对感染的瓣膜进行手术置换以消除感染。
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