Evaluation of the electrosleep machine.

Seven dogs were intensively studied to determine the clinical, physiological, biochemical, and pathological effects of the electrosleep machine. Both the normal dose and a high dose of current was studied. The most notable finding was an increasing number of histologic findings with increasing current dose. There is some question regarding the true nature of these findings. Other changes which were less definite included: EEG slowing and depression of the amplitude of the B-wave in the ERG. Suggestive changes included a chronic increase in pulse rate. Because of the small number of subjects, further studies are indicated to investigate further the findings of this study.