经皮睾丸精子抽吸术及卵胞浆内单精子注射术治疗重度男性不育症
[Percutaneous testicular sperm aspiration and intracytoplasmic sperm injection in the treatment of severe male infertility].
作者信息
Cao Y, Cao X, Han J
机构信息
Embryo Laboratory, Shanghai JiAi Genetics and In-Vitro Fertilization Institute, Shanghai 200011, China.
出版信息
Zhonghua Fu Chan Ke Za Zhi. 2001 Nov;36(11):666-8.
OBJECTIVE
To investigate the efficacy of intracytoplasmic sperm injection (ICSI) combined with percutaneous testicular sperm aspiration (PTSA) in the treatment of severe male infertility.
METHODS
From October 1998 to December 2000, 162 couples were enrolled, and ICSI and PTSA were adopted. Ovarian stimulation was achieved by the short protocol. All metaphase II (M II) oocytes were selected for ICSI.
RESULTS
1,517 M II oocytes were injected in 185 cycles, 990 fertilized (65.3%), and 152 embryo implanted. 54 couples achieved clinical pregnancy (35.5%).
CONCLUSION
PTSA combined with ICSI is a rapid, convenient, painless and effective approach for the treatment of severe male infertility.
目的
探讨卵胞浆内单精子注射（ICSI）联合经皮睾丸精子抽吸术（PTSA）治疗严重男性不育症的疗效。
方法
1998年10月至2000年12月，纳入162对夫妇，采用ICSI和PTSA。采用短方案进行卵巢刺激。所有中期II（M II）卵母细胞均被选用于ICSI。
结果
在185个周期中注射了1517个M II卵母细胞，990个受精（65.3%），152个胚胎着床。54对夫妇实现临床妊娠（35.5%）。
结论
PTSA联合ICSI是治疗严重男性不育症的一种快速、便捷、无痛且有效的方法。
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