Jiang J, Wang Y, Chen F
Department of Vascular Surgery, Zhongshan Hospital, Fudan University Medical College, Shanghai 200032, China.
Zhonghua Wai Ke Za Zhi. 2001 Nov;39(11):829-31.
To study the early mortality and major complications of infrarenal abdominal aortic aneurysm (AAA) repair.
One hundred and eighty-six cases of infrarenal AAA, which underwent surgery in our hospital between January 1988 and December 2000, were selected. Early mortality and major complications were rated, and preoperative cardiac, pulmonary and renal condition, age and surgical impact were taken into account while evaluating the risk factors of early mortality and major complications.
The early mortality was 5.0% for elective surgery and 57.1% for ruptured surgery. The early major complication rate for AAA repair was 18.4% in total, and 10.6%, 11.2%, 2.8%, 1.1% for cardiac complication, pulmonary complication, acute renal failure, stroke and hepatic insufficiency respectively. Coronary heart disease significantly predisposed the patients to the development of cardiac complications (chi 2 = 19.737, P < 0.01) while hypertension had no such effect (chi 2 = 1.870, P > 0.05). Abnormal pulmonary function, smoking and PaO2 less than 80 mmHg were responsible for postoperative pneumonia(chi 2 = 4.051, 5.885 and 5.162, P < 0.05), but not for adult respiratory distress syndrome(chi 2 = 0.127, 0.916 and 1.067, P > 0.05). Preoperative renal function was not related postoperative acute renal failure(chi 2 = 0.404, P > 0.05). Age more than 70 years or operation spanned more than 5 hours increased major complications(chi 2 = 16.119 and 10.163, P < 0.01) and early mortality(chi 2 = 16.119 and 10.163, P < 0.01).
Multiple system organ failure is the leading cause of early mortality of AAA repair. Cardiac and pulmonary complications are commonly seen after AAA repair. Preoperative cardiac, pulmonary condition, age and surgical aspects greatly influence the early mortality and major complications.
研究肾下腹主动脉瘤(AAA)修复术的早期死亡率及主要并发症。
选取1988年1月至2000年12月间在我院接受手术的186例肾下腹主动脉瘤患者。对早期死亡率和主要并发症进行评定,并在评估早期死亡率和主要并发症的危险因素时考虑术前心脏、肺和肾脏状况、年龄及手术影响。
择期手术的早期死亡率为5.0%,破裂手术的早期死亡率为57.1%。AAA修复术的早期主要并发症总发生率为18.4%,其中心脏并发症、肺部并发症、急性肾衰竭、中风和肝功能不全的发生率分别为10.6%、11.2%、2.8%、1.1%。冠心病显著增加患者发生心脏并发症的风险(χ² = 19.737,P < 0.01),而高血压无此作用(χ² = 1.870,P > 0.05)。肺功能异常、吸烟及动脉血氧分压(PaO₂)低于80 mmHg是术后肺炎的相关因素(χ² = 4.051、5.885和5.162,P < 0.05),但与成人呼吸窘迫综合征无关(χ² = 0.127、0.916和1.067,P > 0.05)。术前肾功能与术后急性肾衰竭无关(χ² = 0.404,P > 0.05)。年龄超过70岁或手术时间超过5小时会增加主要并发症(χ² = 16.119和10.163,P < 0.01)及早期死亡率(χ² = 16.119和10.163,P < 0.01)。
多系统器官功能衰竭是AAA修复术早期死亡的主要原因。心脏和肺部并发症是AAA修复术后常见的并发症。术前心脏、肺状况、年龄及手术因素对早期死亡率和主要并发症有很大影响。