Fotaki P, Deligeoroglou E, Michailidis E, Vitoratos N, Kokkalis D, Siristatidis X, Creatsas G
Fetal-Maternal Unit, 2nd Obstetrics and Gynecology Department, Aretaieion Hospital, University of Athens, Greece.
Akush Ginekol (Sofiia). 2002;42(1):38-9.
Is introducing a case study on a 20 year old female first time pregnant who presents with rare case of Adamantiadis-Bechet syndrome. These symptoms first appeared at the age of 9. The patient refers that from this age she has suffered from recurrent relapses of ulcerations of the mouth and genital organs, vescicular exanthema of the upper and lower extremities and severe headaches that would not subside with analgetic therapy. The patient upon the first trimester presented with a relapse of the disease and significant improvement during the remainder of the pregnancy. She delivered on the 39th week of her pregnancy a neonate male, alive and weighing 3640 gr. The Apgar--score 9 and 10 the 1st and 5th minute. Mother and neonate were discharged from the clinic on the 3rd postpartum day in good health. This case is also being discussed in international bibliography. Adamantiadis-Behcet syndrome constitutes systemic angiitis of unknown etiology that is characterized mainly by recurrent ulcers of the mouth and genital organs, serum negative arthritis, central nervous system disorders as well as ulcerations of the epidermis, nodular erythema, thrombophlebitis and vision disorders. It usually affects people in early adulthood, more often those in their 30s. Geographically it is seen more often in Japan, Korea, Turkey, Israel and other Mediterranean countries. Familial prevalence is also common.
现介绍一例20岁初孕女性病例,该患者患有罕见的亚当斯-贝切特综合征。这些症状首次出现于9岁。患者自述从这个年龄起,她就反复出现口腔和生殖器溃疡、上下肢水疱性皮疹以及严重头痛,且镇痛治疗无法缓解。患者在孕早期疾病复发,而在孕期其余时间病情显著改善。她在怀孕第39周产下一名男婴,新生儿存活,体重3640克。阿氏评分在第1分钟和第5分钟分别为9分和10分。母亲和新生儿在产后第3天健康出院。该病例也在国际文献中被讨论。亚当斯-贝切特综合征是一种病因不明的系统性血管炎,主要特征为反复出现的口腔和生殖器溃疡、血清阴性关节炎、中枢神经系统疾病以及表皮溃疡、结节性红斑、血栓性静脉炎和视力障碍。它通常在成年早期发病,多见于30多岁的人群。在地理上,日本、韩国、土耳其、以色列和其他地中海国家更为常见。家族患病率也很常见。