Sandoval Claudio, Berger Emily, Ozkaynak M Fevzi, Tugal Oya, Jayabose Somasundaram
Department of Pediatrics, New York Medical College, Valhalla 10595, USA.
Pediatr Hematol Oncol. 2002 Apr-May;19(3):157-61. doi: 10.1080/088800102753541305.
The objective of this study was to determine the clinical and laboratory features of children with severe iron deficiency anemia. The authors retrospectively reviewed the charts of 198 children with iron deficiency anemia to ascertain cases of severe iron deficiency anemia. Forty-two children with severe iron deficient anemia were evaluated. The median age was 21 months (range, 7-240 months) at diagnosis and 27 children were 13-24 months of age. For 35 children the major source of calories was derived from cow's milk. The median hemoglobin was 4.6 g/dL (range, 2.1-6 g/dL) and the median serum ferritin was 5 microg/L (range, 1-11 microg/L). Twenty-nine received oral iron and 13 required parked red blood cell transfusions because of co-morbid cardiorespiratory distress. Severe iron deficiency anemia mostly affects children during their second year of life. Oral iron therapy is sufficient for most children, but packed red blood cell transfusions may be needed.
本研究的目的是确定重度缺铁性贫血患儿的临床和实验室特征。作者回顾性查阅了198例缺铁性贫血患儿的病历，以确定重度缺铁性贫血病例。对42例重度缺铁性贫血患儿进行了评估。诊断时的中位年龄为21个月（范围7 - 240个月），27例患儿年龄在13 - 24个月之间。35例患儿的主要热量来源是牛奶。中位血红蛋白为4.6 g/dL（范围2.1 - 6 g/dL），中位血清铁蛋白为5 μg/L（范围1 - 11 μg/L）。29例接受口服铁剂治疗，13例因合并心肺功能不全需要输注红细胞悬液。重度缺铁性贫血主要影响1 - 2岁的儿童。大多数患儿口服铁剂治疗就足够了，但可能需要输注红细胞悬液。
