Selmani Ziane, Pyykkö Ilmari, Ishizaki Hisayoshi, Ashammakhi Nureddin
Department of Ear, Nose and Throat Diseases, Satakunta Central Hospital, Pori, Finland.
Acta Otolaryngol. 2002 Mar;122(2):173-8. doi: 10.1080/00016480252814180.
From an otological standpoint, Lyme disease can manifest itself as Ménière's disease both clinically and electrophysiologically. The aim of this study was to describe the findings of routine clinical, auditory and vestibular tests in patients with Ménière's and Lyme disease and to use electrocochleography (ECoG) to assess the presence of endolymphatic hydrops (EH) in both diseases. Transtympanic ECoG was performed in 91 patients with Ménière's disease and in 11 patients with confirmed Lyme disease. In both diseases the majority of patients had more than one complaint. There was one case with isolated hearing loss in the Lyme disease group. Typical clinical manifestations of Ménière's disease (vertigo, sensorineural hearing loss and tinnitus) were found in 6/11 patients (54.5%) in the Lyme disease group. The ECoG results indicated that there were 65/91 patients (71.4%) with Ménière's disease and 5 patients (45.5%) with Lyme disease who presented with EH. No statistically significant difference was found between the incidence of different symptoms of Ménière's and Lyme disease. On the basis of these results, patients with Lyme disease should undergo careful examination and investigation, especially in endemic regions. The presence of EH does not exclude the presence of infection with borreliosis as a cause of Ménière's disease-like symptoms.
从耳科学角度来看，莱姆病在临床和电生理方面均可表现为梅尼埃病。本研究的目的是描述梅尼埃病和莱姆病患者的常规临床、听觉和前庭测试结果，并使用电耳蜗图（ECoG）评估两种疾病中内淋巴积水（EH）的存在情况。对91例梅尼埃病患者和11例确诊为莱姆病的患者进行了经鼓膜ECoG检查。在这两种疾病中，大多数患者都有不止一种症状。莱姆病组中有1例孤立性听力损失病例。莱姆病组中6/11例患者（54.5%）出现了梅尼埃病的典型临床表现（眩晕、感音神经性听力损失和耳鸣）。ECoG结果显示，梅尼埃病患者中有65/91例（71.4%）、莱姆病患者中有5例（45.5%）存在EH。梅尼埃病和莱姆病不同症状的发生率之间未发现统计学上的显著差异。基于这些结果，莱姆病患者应接受仔细检查和调查，尤其是在流行地区。EH的存在并不排除作为梅尼埃病样症状病因的疏螺旋体感染的存在。
