Kato Masahiro, Sugiura Makoto, Shimono Mariko, Yoshida Tadao, Otake Hironao, Kato Ken, Teranishi Masaaki, Sone Michihiko, Yamazaki Masahiro, Naganawa Shinji, Nakashima Tsutomu
Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Acta Otolaryngol. 2013 Feb;133(2):123-9. doi: 10.3109/00016489.2012.726374. Epub 2012 Oct 29.
Our study showed that patients with atypical Meniere's disease had endolymphatic hydrops (EH) in both the cochlea and the vestibule. Using an imaging method, we provide evidence that atypical Meniere's disease is a true variant of classic Meniere's disease.
The aim of present study was to investigate images of the endolymphatic space in patients with atypical Meniere's disease (cochlear and vestibular Meniere's disease).
Sixty-four patients divided into two groups were enrolled in this study. The first group included 36 patients who had fluctuating hearing loss without vertigo, as candidates for cochlear Meniere's disease (CMD). The second group included 28 patients who had recurrent vertigo without hearing loss, as candidates for vestibular Meniere's disease (VMD). The patients underwent 3 T magnetic resonance imaging (MRI) after injection of gadolinium enhancement medium intratympanically or intravenously. We evaluated EH using MRI.
Of 56 ears (36 patients) with CMD, 38 showed EH in the cochlea and 44 showed EH in the vestibule. Of 56 ears (28 patients) with VMD, 29 showed EH in the cochlea and 47 showed EH in the vestibule. The VMD group had a significant vestibular predominance in EH distribution whereas the CMD group showed no significant regional predominance of EH.
我们的研究表明，非典型梅尼埃病患者的耳蜗和前庭均存在内淋巴积水（EH）。通过一种成像方法，我们提供了证据表明非典型梅尼埃病是经典梅尼埃病的一种真正变体。
本研究的目的是调查非典型梅尼埃病（耳蜗性和前庭性梅尼埃病）患者内淋巴间隙的影像。
本研究纳入了分为两组的64例患者。第一组包括36例有波动性听力损失但无眩晕的患者，作为耳蜗性梅尼埃病（CMD）的候选者。第二组包括28例有反复眩晕但无听力损失的患者，作为前庭性梅尼埃病（VMD）的候选者。患者在经鼓膜或静脉注射钆增强介质后接受3T磁共振成像（MRI）检查。我们使用MRI评估EH。
在56只耳朵（36例患者）的CMD中，38只在耳蜗显示EH，44只在前庭显示EH。在56只耳朵（28例患者）的VMD中，29只在耳蜗显示EH，47只在前庭显示EH。VMD组在EH分布上有明显的前庭优势，而CMD组在EH上未显示出明显的区域优势。
