Al-Khuwaitir Tarig S, Wani Bashir A, Sherbeeni Suphia M
Department of Medicine, Riyadh Medical Complex, PO Box 3847, Riyadh 11481, Kingdom of Saudi Arabia.
Saudi Med J. 2002 Jan;23(1):99-103.
Infectious endocarditis is a potentially lethal inflammation of the hearts' inner lining invaded by microorganisms. The mortality from this illness increases as the number of infective organisms rises to 2, due to involvement of the left side of the heart. These microorganisms usually arise from the patient's own flora but can be acquired from the environment. Fever and heart murmurs are the principal clinical manifestations followed by a plethora of peripheral signs due to dissemination of microorganisms via the bloodstream. Echocardiographic imaging and sensitive culture techniques form the cornerstone of diagnosis. We report a patient with rheumatic heart disease who had combined brucella melitensis and streptococcus viridans endocarditis complicated by heart failure and an aortic root abscess. He was diagnosed on the basis of a history of prolonged fever and occupational risk as a shepherd, the presence of heart murmurs, positive blood cultures and echocardiographic evidence of aortic vegetations. He had an excellent response to intravenous antibiotic therapy combined with aortic valve replacement, which nowadays is regarded as the safest therapeutic approach for aortic valve endocarditis.
感染性心内膜炎是心脏内膜被微生物侵袭后发生的一种潜在致命性炎症。随着感染性生物体数量增至2种,由于心脏左侧受累,这种疾病的死亡率会升高。这些微生物通常源于患者自身的菌群,但也可能从环境中获得。发热和心脏杂音是主要临床表现,随后因微生物通过血流播散而出现大量外周体征。超声心动图成像和敏感的培养技术是诊断的基石。我们报告一名风湿性心脏病患者,其合并有羊布鲁氏菌和草绿色链球菌心内膜炎,并伴有心力衰竭和主动脉根部脓肿。根据长期发热病史、作为牧羊人所面临的职业风险、心脏杂音的存在、血培养阳性以及主动脉赘生物的超声心动图证据,他被确诊。他对静脉抗生素治疗联合主动脉瓣置换术反应良好,如今这被视为主动脉瓣心内膜炎最安全的治疗方法。