Klapheke Martin M.
The Menninger Clinic, Topeka, Kansas, USA.
Convuls Ther. 1993;9(4):241-255.
A comprehensive review describes the benefits and risks of the combination of electroconvulsive therapy (ECT) and antipsychotic agents for patients with psychotic disorders. For some patients, combined treatment may lead to greater rates of response or more rapid improvement than with either therapy alone. Except for reserpine, combining neuroleptics with ECT is safe, but some precautions are suggested. The mechanism of interaction, effect on seizure threshold, the use of ECT for neuroleptic associated motor effects, and additional anesthesia considerations are discussed.
一项全面综述描述了电休克疗法（ECT）与抗精神病药物联合使用对精神障碍患者的益处和风险。对于一些患者，联合治疗可能比单独使用任何一种疗法产生更高的缓解率或更快的改善。除利血平外，将抗精神病药物与ECT联合使用是安全的，但建议采取一些预防措施。文中讨论了相互作用机制、对癫痫阈值的影响、ECT用于抗精神病药物相关运动效应以及额外的麻醉注意事项。
