克雅氏病一例的序列磁共振成像
Sequential MRI in a case of Creutzfeldt-Jakob disease.
作者信息
Tribl G G, Strasser G, Zeitlhofer J, Asenbaum S, Jarius C, Wessely P, Prayer D
机构信息
Universitätsklinik für Neurologie, Allgemeines Krankenhaus Wien, Währinger Gürtel, Vienna, Austria.
出版信息
Neuroradiology. 2002 Mar;44(3):223-6. doi: 10.1007/s002340100695.
A 48-year-old man suddenly developed clinically and electroencephalographically nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes appeared only 9 months after the onset. Brain biopsy confirmed Creutzfeldt-Jakob disease (CJD). In rapidly progressive dementia, we recommend DWI for early diagnosis of CJD.
一名48岁男性突然出现临床和脑电图表现均无特异性的痴呆症状。在MRI序列中，仅皮质的弥散加权成像（DWI）有明确的病理学表现。明显的萎缩和基底节信号改变在起病9个月后才出现。脑活检确诊为克雅氏病（CJD）。对于快速进展性痴呆，我们建议采用DWI进行CJD的早期诊断。
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