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实施美国心脏病学会/美国心脏协会(ACC/AHA)针对计划进行非心脏手术的冠心病患者术前管理的指南:对围手术期结局的影响。

Implementing ACC/AHA guidelines for the preoperative management of patients with coronary artery disease scheduled for noncardiac surgery: effect on perioperative outcome.

作者信息

Farid Ibrahim, Litaker David, Tetzlaff John E

机构信息

Department of General Anesthesiology, The Cleveland Clinic Foundation, OH 44195, USA.

出版信息

J Clin Anesth. 2002 Mar;14(2):126-8. doi: 10.1016/s0952-8180(01)00367-1.

Abstract

STUDY OBJECTIVE

To review the new consensus guidelines for cardiac testing for the patient with cardiac disease scheduled for elective, noncardiac surgery, and their impact on cardiac functional testing.

DESIGN

Retrospective chart review study.

SETTING

Tertiary care medical center.

PATIENTS

181 patients scheduled for elective, major surgery who met American College of Cardiology/American Heart Association (ACC/AHA) criteria for a preoperative stress test.

INTERVENTIONS

A variety of tests were ordered, including treadmill stress testing, persantine-thallium imaging, dobutamine echocardiography, and exercise stress echocardiography.

MEASUREMENTS

The numbers of and outcome of the stress tests and the cardiac outcome of the patients who underwent cardiac testing and surgery were recorded.

MAIN RESULTS

Abnormal tests occurred in 27 patients. Two patients declined treatment, eight patients had primary medical management, and the remainder (17) had cardiac catheterization. Results included no lesion (2 patients), angioplasty (4 patients), angioplasty plus stenting (1 patient), coronary artery bypass grafting (CABG) (4 patients), and delineated lesions treated with medical optimization (6 patients). One patient had CABG and declined further surgery. One patient had myocardial infarction 6 months after surgery that was treated by medical management after cardiac catheterization. The other 23 patients had surgery without cardiac complication within 1 year of surgery. Only 15% (27/180) of the patients with indications for a stress test had a positive result. Even fewer patients had any alteration of the perioperative period. Despite this finding, cardiac morbidity was very low.

CONCLUSIONS

The guidelines for stress test may be over-sensitive, and further prospective clinical studies are indicated.

摘要

研究目的

回顾针对计划进行择期非心脏手术的心脏病患者的心脏检查新共识指南,以及这些指南对心脏功能测试的影响。

设计

回顾性图表审查研究。

地点

三级医疗中心。

患者

181名计划进行择期大手术且符合美国心脏病学会/美国心脏协会(ACC/AHA)术前应激试验标准的患者。

干预措施

安排了多种检查,包括跑步机应激试验、潘生丁-铊显像、多巴酚丁胺超声心动图和运动应激超声心动图。

测量指标

记录应激试验的数量和结果,以及接受心脏检查和手术患者的心脏结局。

主要结果

27例患者检查结果异常。2例患者拒绝治疗,8例患者接受主要药物治疗,其余17例接受心脏导管插入术。结果包括无病变(2例)、血管成形术(4例)、血管成形术加支架置入术(1例)、冠状动脉旁路移植术(CABG)(4例),以及通过药物优化治疗的明确病变(6例)。1例患者接受CABG后拒绝进一步手术。1例患者术后6个月发生心肌梗死,经心脏导管插入术后药物治疗。其他23例患者在术后1年内手术,无心脏并发症。有应激试验指征的患者中只有15%(27/180)结果呈阳性。围手术期有改变的患者更少。尽管有这一发现,但心脏发病率非常低。

结论

应激试验指南可能过于敏感,需要进一步开展前瞻性临床研究。

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