Schwartz Harry C, Kagan A Robert
Department of Maxillofacial Surgery, Southern California Permanente Medical Group, Los Angeles, California, USA.
Am J Clin Oncol. 2002 Apr;25(2):168-71. doi: 10.1097/00000421-200204000-00013.
Osteoradionecrosis of the mandible can be a serious complication of radiotherapy for head and neck cancer. The disorder generally presents in one of several distinct clinical variations. This is probably because of a complex interaction of etiologic factors. A clinical staging system for the disorder is described. Such a system is necessary for the conduct of clinical research, and for the development and assessment of treatment regimens.
下颌骨放射性骨坏死可能是头颈癌放疗的严重并发症。该病症通常以几种不同的临床变体之一出现。这可能是由于病因因素的复杂相互作用。本文描述了该病症的临床分期系统。这样的系统对于开展临床研究以及制定和评估治疗方案是必要的。
