Epstein J B, Wong F L, Stevenson-Moore P
J Oral Maxillofac Surg. 1987 Feb;45(2):104-10. doi: 10.1016/0278-2391(87)90399-5.
Osteoradionecrosis is a severe complication of radiation therapy for cancer. Prevention of osteoradionecrosis is most important as the condition may be chronic, progressive and lead to pathologic fracture. The clinical experience at the Cancer Control Agency of British Columbia with 26 cases in approximately 1000 patients treated with radical radiation therapy to the head and neck region is presented and discussed. A clinical classification system is proposed to provide a guide for treatment selection, and to allow classification for research purposes.
放射性骨坏死是癌症放射治疗的一种严重并发症。预防放射性骨坏死最为重要，因为这种病症可能是慢性、进行性的，并会导致病理性骨折。本文介绍并讨论了不列颠哥伦比亚癌症控制机构对约1000例接受头颈部根治性放射治疗的患者中的26例的临床经验。提出了一种临床分类系统，以指导治疗选择，并便于进行研究分类。
