Krysenko A V, Skliar T V, Kozitskaia S N, Golodok L P, Vinnikov A I
Dniepropetrovsk State University, 13 Naukovy Lane, Dniepropetrovsk, 49050, Ukraine.
Mikrobiol Z. 2001 Nov-Dec;63(6):19-24.
A higher rate of glucose oxidation by antibiotic-resistant staphylococcus and gonococcus strains has been established; at the same time the sensitive strains are characterised by more intensive oxidation of pyruvate and acetate as compared with the resistant strains. High rate of lactate accumulation by antibiotic-resistant strains has been marked for the studied staphylococci strains. Antibiotic-resistant strains of gonococci are characterised by more intensive accumulation of acetate as the end product of glucose catabolism. No significant differences were revealed for the stable and sensitive strains of gonococci as to the rate of acetate involving in metabolic processes, but a steady tendency to the increase of acetate consumption intensity is observed.
已证实抗生素耐药性葡萄球菌和淋球菌菌株的葡萄糖氧化率较高；与此同时，与耐药菌株相比，敏感菌株的丙酮酸和乙酸氧化更为强烈。在所研究的葡萄球菌菌株中，已发现抗生素耐药菌株的乳酸积累率较高。淋病奈瑟菌的抗生素耐药菌株的特征是作为葡萄糖分解代谢终产物的乙酸积累更为强烈。淋病奈瑟菌的稳定菌株和敏感菌株在乙酸参与代谢过程的速率方面未显示出显著差异，但观察到乙酸消耗强度有稳步增加的趋势。
