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[淋病奈瑟菌菌株中对抗生素耐药和敏感的三羧酸循环酶的活性]

[Activity of enzymes of the tricarboxylic acid cycle in Neisseria gonorrhoeae strains resistant and sensitive to antibiotics].

作者信息

Krysenko O V, Vinnikov A I

出版信息

Mikrobiol Z. 2004 Nov-Dec;66(6):3-9.

Abstract

The activity of enzymes of the tricarboxylic acid cycle and some enzymes which catalyze the reactions connected with the reactions cycle of Neisseria gonorrhoeae strains which contain plasmids with various spectrum and level of sensitivity to antibiotics has been studied. The decrease of activity of the basic enzymes of the cycle and intensification of anapleurotic reactions and reactions of constructive metabolism connected with the tricarboxylic acid cycle in antibiotic-resistant containing plasmids strains has been found.

摘要

对淋病奈瑟菌菌株中三羧酸循环的酶以及一些催化与反应循环相关反应的酶的活性进行了研究,这些菌株含有对不同抗生素具有不同敏感性谱和水平的质粒。已发现含质粒的抗生素抗性菌株中,循环基本酶的活性降低,与三羧酸循环相关的回补反应和建设性代谢反应增强。

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