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[口腔黏膜大疱性疾病]

[Bullous diseases of the oral mucosa].

作者信息

Vaillant Loïc, Fontès Valérie

机构信息

Service de dermatologie et consultation de dermatologie buccale hôpital Trousseau CHRU 37044 Tours.

出版信息

Rev Prat. 2002 Feb 15;52(4):385-8.

Abstract

Bullous diseases of the oral cavity cause painful, erosive lesions. These must be distinguished from aphthous ulcers and vesicles with which they are often confused. The causes of post-bullous erosions are varied. Acute lesions can be due to trauma, erythema multiforme or toxidermia. The examination of the skin and the medical history are the keys to diagnosis. Chronic bullous diseases can be due to congenital diseases (epidermolysis bullosa or lymphangioma), which are easily evoked by the age at which the symptoms appear and the clinical picture. Acquired chronic bullous diseases include lichen planus and bullous auto-immune diseases. The keys to diagnosis are the presence of other mucosal or cutaneous lesions, the histological examination and the finding of perilesional antibodies on the mucosa. The symptomatic treatment of oral bullous lesions includes the following of a specific diet, use of antalegics and the prevention or treatment of superimposed infection.

摘要

口腔大疱性疾病会导致疼痛性糜烂性病变。这些病变必须与常常与之混淆的阿弗他溃疡和水疱相区分。大疱后糜烂的病因多种多样。急性病变可能由创伤、多形红斑或中毒性表皮坏死松解症引起。皮肤检查和病史是诊断的关键。慢性大疱性疾病可能由先天性疾病(大疱性表皮松解症或淋巴管瘤)引起,这些疾病很容易根据症状出现的年龄和临床表现推断出来。后天性慢性大疱性疾病包括扁平苔藓和自身免疫性大疱病。诊断的关键在于是否存在其他黏膜或皮肤病变、组织学检查以及在黏膜上发现损害周围抗体。口腔大疱性病变的对症治疗包括遵循特定饮食、使用止痛剂以及预防或治疗叠加感染。

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