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腰骶部转移性硬膜外默克尔细胞癌致神经根受压——病例报告

Lumbosacral metastatic extradural Merkel cell carcinoma causing nerve root compression--case report.

作者信息

Turgut Mehmet, Gökpinar Deniz, Barutça Sabri, Erkuş Muhan

机构信息

Neurosurgery Department, Adnan Menderes University Hospital, Aydin, Turkey.

出版信息

Neurol Med Chir (Tokyo). 2002 Feb;42(2):78-80. doi: 10.2176/nmc.42.78.

Abstract

A 63-year-old man presented with a rare metastatic Merkel cell carcinoma (MCC) involving the lumbosacral spine and causing nerve root compression. Magnetic resonance (MR) imaging revealed an extradural soft tissue mass at the L5-S1 levels. The tumor was subtotally removed and chemotherapy was administered, but he died of multiple metastases from the primary epigastric tumor. Lumbosacral metastatic epidural tumor can manifest as lumbar disc disease symptoms, but MR imaging can non-invasively and rapidly reveal the presence of spinal epidural tumor and any extension to the spinal canal. Extradural MCC metastasis in the lumbosacral area should be considered in the differential diagnosis of radicular symptoms caused by disc herniation.

摘要

一名63岁男性患者,患有罕见的转移性默克尔细胞癌(MCC),累及腰骶椎并导致神经根受压。磁共振(MR)成像显示L5-S1水平有硬膜外软组织肿块。肿瘤被次全切除并进行了化疗,但他死于原发性上腹部肿瘤的多处转移。腰骶部转移性硬膜外肿瘤可表现为腰椎间盘疾病症状,但MR成像可无创且快速地显示脊柱硬膜外肿瘤的存在及其向椎管的任何延伸情况。在因椎间盘突出症引起的神经根症状的鉴别诊断中,应考虑腰骶部硬膜外MCC转移。

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