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脊髓损伤中的肺不张和黏液阻塞:病例报告及治疗方法

Atelectasis and mucus plugging in spinal cord injury: case report and therapeutic approaches.

作者信息

Slonimski M, Aguilera E J

机构信息

Department of Rehabilitation Medicine, West Roxbury Veterans Affairs Medical Center, Massachusetts 02132, USA.

出版信息

J Spinal Cord Med. 2001 Winter;24(4):284-8. doi: 10.1080/10790268.2001.11753586.

Abstract

INTRODUCTION

The leading causes of morbidity and mortality in the spinal cord injury (SCI) population are airway mucus plugging and atelectasis.

OBJECTIVE

To illustrate the risks of pulmonary disease in individuals with SCI, and present effective therapeutic interventions.

DESIGN

Case study of a 60-year-old veteran with T7 ASIA A spinal cord injury, who presented with a complete collapse of the left lung.

FINDINGS

This patient developed fever, sepsis, and acute renal failure following colonoscopy. Following nephrostomy to remove a calculus, chest x-ray revealed complete collapse of the left lung. Despite the severe degree of atelectasis, he exhibited only mild respiratory distress. Aggressive treatment including chest physiotherapy techniques and pharmacologic intervention (acetylcysteine; bronchodilators) resulted in significant radiographic and clinical improvement. After his return to the SCI unit, his respiratory function was monitored, and assisted cough techniques were continued.

CONCLUSIONS

Individuals with SCI have high risk of pulmonary complications. Because of neurological deficits, the usual signs and symptoms may not be apparent. Optimal management depends upon awareness of the risks, and a thorough understanding of the pathophysiology of mucus plugging and atelectasis and the alterations in pulmonary mechanics (dependent on level of injury).

摘要

引言

脊髓损伤(SCI)人群发病和死亡的主要原因是气道黏液阻塞和肺不张。

目的

阐述SCI患者发生肺部疾病的风险,并介绍有效的治疗干预措施。

设计

对一名60岁、T7级亚洲损伤分级A的脊髓损伤退伍军人进行病例研究,该患者出现左肺完全萎陷。

研究结果

该患者在结肠镜检查后出现发热、脓毒症和急性肾衰竭。在进行肾造瘘术以取出结石后,胸部X线显示左肺完全萎陷。尽管肺不张程度严重,但他仅表现出轻度呼吸窘迫。包括胸部物理治疗技术和药物干预(乙酰半胱氨酸;支气管扩张剂)在内的积极治疗使影像学和临床症状有了显著改善。回到脊髓损伤病房后,对其呼吸功能进行了监测,并继续采用辅助咳嗽技术。

结论

SCI患者发生肺部并发症的风险很高。由于神经功能缺损,通常的体征和症状可能不明显。最佳治疗取决于对风险的认识,以及对黏液阻塞和肺不张的病理生理学以及肺力学改变(取决于损伤水平)的透彻理解。

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