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Interconversion of pyruvate dehydrogenase in rat heart muscle upon perfusion with fatty acids or ketone bodies.

作者信息

Wieland O, Funcke H v., Löffler G

机构信息

Institute of Clinical Chemistry, Schwabing City Hospital and Diabetes Research Unit, Munich, Germany

出版信息

FEBS Lett. 1971 Jul 1;15(4):295-298. doi: 10.1016/0014-5793(71)80641-5.

DOI:10.1016/0014-5793(71)80641-5
PMID:11945867
Abstract
摘要

相似文献

1
Interconversion of pyruvate dehydrogenase in rat heart muscle upon perfusion with fatty acids or ketone bodies.大鼠心肌中丙酮酸脱氢酶在脂肪酸或酮体灌注时的相互转化。
FEBS Lett. 1971 Jul 1;15(4):295-298. doi: 10.1016/0014-5793(71)80641-5.
2
Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide.大鼠心脏中丙酮酸脱氢酶的调节。脂肪酸和酮体氧化对去磷酸化和磷酸化酶比例的调节机制以及糖尿病的影响:辅酶A、乙酰辅酶A以及还原型和氧化型烟酰胺腺嘌呤二核苷酸的作用
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Effect of insulin on ketogenesis and fatty acid synthesis in rat hepatocytes incubated with dichloroacetate.胰岛素对用二氯乙酸孵育的大鼠肝细胞中酮体生成和脂肪酸合成的影响。
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Studies on the influence of fatty acids on pyruvate dehydrogenase interconversion in rat-liver mitochondria.脂肪酸对大鼠肝脏线粒体中丙酮酸脱氢酶相互转化影响的研究。
Eur J Biochem. 1976 Dec;71(1):229-37. doi: 10.1111/j.1432-1033.1976.tb11109.x.
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Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles.肌肉对葡萄糖摄取的调节。9. 脂肪酸、酮体、四氧嘧啶糖尿病和饥饿对大鼠心脏和大鼠膈肌中丙酮酸代谢以及乳酸-丙酮酸和L-甘油3-磷酸-二羟丙酮磷酸浓度比的影响。
Biochem J. 1964 Dec;93(3):665-78. doi: 10.1042/bj0930665.
6
Effect of fatty acids, ketone bodies, diabetes and starvation on pyruvate metabolism in rat heart and diaphragm muscle.脂肪酸、酮体、糖尿病及饥饿对大鼠心脏和膈肌丙酮酸代谢的影响。
Nature. 1962 Jul 28;195:381-3. doi: 10.1038/195381a0.
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Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes.脂肪酸和酮体对原代培养大鼠肝细胞中细胞色素P450 2B、4A和2E1表达的影响。
Arch Biochem Biophys. 1997 Jan 15;337(2):217-24. doi: 10.1006/abbi.1996.9785.
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Activities of enzymes of fat and ketone-body metabolism and effects of starvation on blood concentrations of glucose and fat fuels in teleost and elasmobranch fish.硬骨鱼和软骨鱼脂肪及酮体代谢酶的活性以及饥饿对其血液中葡萄糖和脂肪燃料浓度的影响。
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Investigations into the direct effects of insulin on hepatic ketogenesis, lipoprotein secretion and pyruvate dehydrogenase activity.胰岛素对肝脏生酮作用、脂蛋白分泌及丙酮酸脱氢酶活性的直接影响的研究。
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Effect of fatty acids and ketones on the activity of pyruvate dehydrogenase in skeletal-muscle mitochondria.脂肪酸和酮对骨骼肌线粒体中丙酮酸脱氢酶活性的影响。
Biochem J. 1983 Sep 15;214(3):725-36. doi: 10.1042/bj2140725.

引用本文的文献

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Loss of Metabolic Flexibility in the Failing Heart.衰竭心脏中代谢灵活性的丧失。
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2
β-Hydroxybutyrate Boosts Mitochondrial and Neuronal Metabolism but is not Preferred Over Glucose Under Activated Conditions.β-羟基丁酸可促进线粒体和神经元代谢,但在激活条件下并不比葡萄糖更具优势。
Neurochem Res. 2017 Jun;42(6):1710-1723. doi: 10.1007/s11064-017-2228-6. Epub 2017 Mar 18.
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β-Hydroxybutyrate in the Brain: One Molecule, Multiple Mechanisms.大脑中的β-羟基丁酸:一种分子,多种机制。
Neurochem Res. 2017 Jan;42(1):35-49. doi: 10.1007/s11064-016-2099-2. Epub 2016 Nov 8.
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Metabolic shifts during aging and pathology.衰老和病理过程中的代谢转变。
Compr Physiol. 2015 Apr;5(2):667-86. doi: 10.1002/cphy.c140041.
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Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate.丙酮酸与生理底物竞争心脏氧化:对用 1-13C 标记的[1-13C]丙酮酸进行研究的影响。
Am J Physiol Heart Circ Physiol. 2010 May;298(5):H1556-64. doi: 10.1152/ajpheart.00656.2009. Epub 2010 Mar 5.
6
Activation of pyruvate dehydrogenase in perfused rat heart by dichloroacetate (Short Communication).二氯乙酸对灌流大鼠心脏丙酮酸脱氢酶的激活(简短通讯)。
Biochem J. 1973 Jun;134(2):651-3. doi: 10.1042/bj1340651.
7
Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation.高心脏能量产生过程中丙酮酸脱氢酶活性和柠檬酸循环中间体的调节
J Physiol. 2005 Jan 15;562(Pt 2):593-603. doi: 10.1113/jphysiol.2004.075713. Epub 2004 Nov 18.
8
Effect of high lipid diet on circadian rhythms of tissue glycogen.高脂饮食对组织糖原昼夜节律的影响。
Experientia. 1980 Sep 15;36(9):1085-6. doi: 10.1007/BF01965984.
9
The regulation of pyruvate oxidation during membrane depolarization of rat brain synaptosomes.大鼠脑突触体膜去极化过程中丙酮酸氧化的调节
Biochem J. 1980 Nov 15;192(2):741-51. doi: 10.1042/bj1920741.
10
Effect of the fatty acid oxidation inhibitor 2-tetradecylglycidic acid on pyruvate dehydrogenase complex activity in starved and alloxan-diabetic rats.脂肪酸氧化抑制剂2-十四烷基缩水甘油酸对饥饿和四氧嘧啶糖尿病大鼠丙酮酸脱氢酶复合体活性的影响。
Biochem J. 1982 Oct 15;208(1):53-60. doi: 10.1042/bj2080053.