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[学龄前儿童中度蛋白质-能量营养不良对各项生化指标的影响。利用生化指标早期检测营养不良]

[Effect of moderate protein-energy malnutrition in preschool children on various biochemical parameters. Use of biochemical indicators for early detection of malnutrition].

作者信息

Delpeuch F, Cornu A, Chevalier P

出版信息

Ann Nutr Aliment. 1979;33(3):429-41.

PMID:119462
Abstract

The efficiency of several biochemical parameters as indicators of moderate protein-energy malnutrition was investigated. 810 children aged under 5 years were studied in the forest region of southern Cameroon. The children were divided into groups of controls children and moderately malnourished children based on anthropometry. The means values of most of the biochemical parameters were decreased in the malnourished group. Prealbumin, Transferrin, Hydroxyproline index and Albumin/Globulins ratio showed the most significant decreases. There were highly significant (P less than 0.001) correlations between the parameters and all the anthropometric tests. It is concluded that biochemical tests studied are of value in detection of mild protein-energy malnutrition but only when used together and compared with levels in a control group of the same age and the same population. Because of the slight decreases, large distributions of individual values and interaction of factors others than malnutrition, interpretation of a single test appears to be very complex.

摘要

研究了几种生化参数作为中度蛋白质 - 能量营养不良指标的有效性。在喀麦隆南部森林地区对810名5岁以下儿童进行了研究。根据人体测量学将儿童分为对照组和中度营养不良组。营养不良组中大多数生化参数的均值下降。前白蛋白、转铁蛋白、羟脯氨酸指数和白蛋白/球蛋白比值下降最为显著。这些参数与所有人体测量测试之间存在高度显著(P小于0.001)的相关性。得出的结论是,所研究的生化测试在检测轻度蛋白质 - 能量营养不良方面具有价值,但前提是要一起使用并与同年龄、同人群的对照组水平进行比较。由于下降幅度较小、个体值分布较广以及除营养不良外其他因素的相互作用,单一测试的解读似乎非常复杂。

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