Lemonnier D, Acher S, Boukaïba N, Flament C, Doucet C, Piau A, Chappuis P
INSERM Unité 1, Hôpital Bichat, Paris, France.
Eur J Clin Nutr. 1991 Jun;45(6):281-6.
Institutionalized aged subjects, considered free of evolutive disease and whose body weight was stable, were studied. They were divided into two groups depending on their body mass index: controls (BMI greater than or equal to 24) and depleted (BMI less than or equal to 21). The depleted group, as judged by anthropometric measurements, showed dramatically reduced body muscle and adipose masses. Usual blood parameters were normal in both groups. Biochemical markers of the protein and energy status, viz. albumin, transthyretin, transferrin, somatomedin-C, as well as serum levels of osteocalcin and apolipoproteins AI, AII, B, CII, CIII and E, were not affected in the depleted group. However, moderate iron deficiency and marked zinc deficiency were found in this group. It is concluded that in the elderly, biochemical markers of the protein and energy status are not related to the nutritional status assessed by anthropometry.
对那些被认为没有进行性疾病且体重稳定的老年住院患者进行了研究。根据体重指数将他们分为两组：对照组（体重指数大于或等于24）和消瘦组（体重指数小于或等于21）。通过人体测量判断，消瘦组的身体肌肉和脂肪量显著减少。两组的常规血液参数均正常。蛋白质和能量状态的生化标志物，即白蛋白、转甲状腺素蛋白、转铁蛋白、生长激素介质-C，以及骨钙素和载脂蛋白AI、AII、B、CII、CIII和E的血清水平，在消瘦组中未受影响。然而，该组发现有中度缺铁和明显缺锌。结论是，在老年人中，蛋白质和能量状态的生化标志物与通过人体测量评估的营养状况无关。
