碱性致脑炎蛋白：在磺乙基葡聚糖凝胶上的简化纯化方法 - Suppr

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超能文献

Basic encephalitogenic protein: A simplified purification on sulphoethyl-sephadex.

作者信息

Hirshfeld H, Teitelbaum D, Arnon R, Sela M

机构信息

Department of Chemical Immunology, The Weizmann Institute of Science, Rehovot, Israel

出版信息

FEBS Lett. 1970 May 1;7(4):317-320. doi: 10.1016/0014-5793(70)80193-4.

DOI:10.1016/0014-5793(70)80193-4

PMID:11947503

Abstract

摘要

相似文献

Basic encephalitogenic protein: A simplified purification on sulphoethyl-sephadex.碱性致脑炎蛋白：在磺乙基葡聚糖凝胶上的简化纯化方法

FEBS Lett. 1970 May 1;7(4):317-320. doi: 10.1016/0014-5793(70)80193-4.

The osmotic properties of sulphoethyl-sephadex. A model for cartilage.磺乙基葡聚糖的渗透特性。一种软骨模型。

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Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein.不同的小鼠T细胞受体参与对髓鞘碱性蛋白嵌套表位的自身免疫性致脑炎性反应。

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[Isolation and purification of myelin basic protein from human brain].[从人脑中分离和纯化髓鞘碱性蛋白]

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Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar V alpha and V beta chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different.尽管所识别的主要组织相容性复合体和致脑炎决定簇不同，但针对髓鞘碱性蛋白致脑炎决定簇的大鼠和小鼠T细胞受体都使用相似的Vα和Vβ链基因。

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A cross-reactive idiotope on T cells from PL/J mice and Lewis rats that recognizes different myelin basic protein encephalitogenic epitopes but is restricted by TCR V beta 8.2.来自PL/J小鼠和Lewis大鼠的T细胞上的一种交叉反应性独特型决定簇，其识别不同的髓鞘碱性蛋白致脑炎表位，但受TCR Vβ8.2限制。

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Definition of encephalitogenic and immunodominant epitopes of guinea pig myelin basic protein (Gp-BP) in Lewis rats tolerized neonatally with Gp-BP or Gp-BP peptides.用豚鼠髓鞘碱性蛋白（Gp-BP）或Gp-BP肽对新生Lewis大鼠进行耐受处理后，豚鼠髓鞘碱性蛋白（Gp-BP）的致脑炎性和免疫显性表位的定义。

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Major role of antigen-presenting cells in the response of rat encephalitogenic T cells to myelin basic proteins.抗原呈递细胞在大鼠致脑炎性T细胞对髓鞘碱性蛋白反应中的主要作用。

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Experimental allergic encephalomyelitis. Isolation of basic proteins and polypeptides from central nervous tissue.实验性变应性脑脊髓炎。从中枢神经组织中分离碱性蛋白和多肽。

Biochem J. 1967 Nov;105(2):559-68. doi: 10.1042/bj1050559.

[Isolation and analysis of encephalitogenic fractions of spinal cord proteins].[脊髓蛋白致脑炎组分的分离与分析]

Vopr Med Khim. 1978 Jan-Feb;24(1):57-62.

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Immunomodulation of experimental autoimmune encephalomyelitis by oral administration of copolymer 1.口服共聚物1对实验性自身免疫性脑脊髓炎的免疫调节作用

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3842-7. doi: 10.1073/pnas.96.7.3842.

Copolymer 1 acts against the immunodominant epitope 82-100 of myelin basic protein by T cell receptor antagonism in addition to major histocompatibility complex blocking.共聚体1除了阻断主要组织相容性复合体外，还通过T细胞受体拮抗作用对抗髓鞘碱性蛋白的免疫显性表位82 - 100。

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):634-9. doi: 10.1073/pnas.96.2.634.

Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis.共聚体1可诱导与髓鞘碱性蛋白发生交叉反应的2型辅助性T细胞，并抑制实验性自身免疫性脑脊髓炎。

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Effect of physical exercise on adoptive experimental auto-immune encephalomyelitis in rats.

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Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells--specificity and promiscuity.髓鞘碱性蛋白与合成共聚物1在活的抗原呈递细胞上与II类主要组织相容性复合体分子的直接结合——特异性与混杂性。

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Antibodies against viruses and structural brain components in oligoclonal IgG obtained from multiple sclerosis brain.从多发性硬化症患者大脑中获得的寡克隆IgG中针对病毒和大脑结构成分的抗体。

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Sensitization against brain gangliosides after therapeutic swine brain implantation in a multiple sclerosis patient.一名多发性硬化症患者接受治疗性猪脑植入后对脑苷脂的致敏反应。

J Neurol. 1986 Feb;233(1):54-6. doi: 10.1007/BF00313994.

Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer Cop 1.合成共聚物Cop 1对T细胞针对髓鞘碱性蛋白反应的特异性抑制作用

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Clinical modeling of T cell vaccination against autoimmune diseases in rats. Selection of antigen-specific T cells using a mitogen.大鼠自身免疫性疾病T细胞疫苗接种的临床建模。使用促有丝分裂原选择抗原特异性T细胞。

J Clin Invest. 1990 May;85(5):1594-8. doi: 10.1172/JCI114610.

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