磺乙基葡聚糖的渗透特性。一种软骨模型。
The osmotic properties of sulphoethyl-sephadex. A model for cartilage.
作者信息
Ogston A G, Wells J D
出版信息
Biochem J. 1972 Jul;128(3):685-90. doi: 10.1042/bj1280685.
Abstract
- Observations are reported on the variation of the swelling of sulphoethyl-Sephadex C-50 and C-25, and of the partition of NaCl between solution and gel, with the concentration of NaCl. 2. The results were interpreted in terms of Manning's (1969) treatment of the interactions between polyionic polymers and simple electrolytes and of Flory's (1953) treatment of the swelling of gels. 3. The results indicate net inner osmotic pressures as high as 3.6x10(5)Pa (140 mosmolar=3.6x10(5)N/m(2)) in 0.15m-NaCl. 4. It is suggested that cartilage may have net inner osmotic pressure of the order of 10(5)Pa.
摘要
- 报道了磺乙基-葡聚糖凝胶C-50和C-25的溶胀变化以及氯化钠在溶液与凝胶之间的分配随氯化钠浓度的变化情况。2. 根据曼宁（1969年）对聚离子聚合物与简单电解质之间相互作用的处理方法以及弗洛里（1953年）对凝胶溶胀的处理方法对结果进行了解释。3. 结果表明，在0.15m氯化钠溶液中，净内部渗透压高达3.6×10⁵帕斯卡（140毫渗摩尔 = 3.6×10⁵牛顿/平方米）。4. 有人提出，软骨可能具有约10⁵帕斯卡的净内部渗透压。
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