Siegers A, Board P N
Department of Anaesthetics, Leighton Hospital, Crewe, UK.
Resuscitation. 2002 Apr;53(1):105-8. doi: 10.1016/s0300-9572(01)00503-2.
We report the case of a 45-year-old woman who had ingested 2000 mg of flecainide with suicidal intent. She developed therapy-resistant ventricular fibrillation (VF) with cardiopulmonary arrest. Cardiopulmonary resuscitation and advanced life support were sustained for 64 min. Following intravenous amiodarone, the patient developed an effective spontaneous rhythm and resumed breathing. An amiodarone infusion was started and continued over a period of 72 h. She recovered completely after 5 days, leaving the hospital without neurological sequelae. Serum flecainide levels approximately 5 h post-ingestion were 850 mg/l. This case report confirms the value of amiodarone in drug-resistant VF, even when the cause may be another antiarrhythmic drug such as flecainide.
我们报告了一例45岁女性病例，该患者出于自杀意图摄入了2000毫克氟卡尼。她出现了对治疗耐药的心室颤动（VF）并伴有心肺骤停。心肺复苏和高级生命支持持续了64分钟。静脉注射胺碘酮后，患者出现了有效的自主心律并恢复了呼吸。开始静脉输注胺碘酮并持续72小时。5天后她完全康复，出院时没有神经后遗症。摄入氟卡尼后约5小时的血清氟卡尼水平为850毫克/升。本病例报告证实了胺碘酮在耐药性室颤中的价值，即使病因可能是另一种抗心律失常药物，如氟卡尼。
