Weitbrecht W-U, Vosskämper Claudia
Neurologische Klinik/KKH, Gummersbach, Akademisches Lehrkrankenhaus für die Universität Köln, Germany.
Fortschr Neurol Psychiatr. 2002 Apr;70(4):178-84. doi: 10.1055/s-2002-24639.
The influence of demographic parameter, the number of different drugs or the frequency of the single doses on the reliability of compliance was subject in different studies. The goal of this investigation was to examine the influence of the drug package information paper on the compliance of neurological-psychiatric patients. 951 patients of one quarter of a neurological-psychiatric practice were given a questionnaire, which examined the income behavior and the estimate of the meaning of the drug package information paper. 352 patients answered the questionnaires. Only 15.6 % refused it to answer the questionnaire. The remaining were not able to answer because of different reasons (dementia, aphasia, acute psychiatric disorders, foreign language origin, immobility, etc.). 98.1 % considered the drug package information paper to be important. Older patients and patients with lower education degree judged the drug package information paper to be too extensive. Only few patients (11.5 %) let the physician explain the drug package information paper. 86.3 % of the patients assumed the medication prescribed by the physician to be correct. 58.1 % of the patients however were not satisfied with the information by the physician. Patients with neuroses were particularly dissatisfied over the clearing-up by the physician (77.3 %). 73.3 % of the patients were deterred from taking in their medicines occasionally or frequently by the side effects described in the drug package information paper. 59.9 % of the patients would take the medicine, if the physician insisted on it. Independently of the influence of the drug package information paper 57.5 % of the patients forgot to take their medicines occasionally or frequently. Patients with epilepsies and M. Parkinson were most compliant. In summary the investigation showed that the clearing-up only by the drug package information paper in contrast to the clearing-up by the physician leads to more non-compliance.
在不同研究中,人口统计学参数、不同药物数量或单次剂量频率对依从性可靠性的影响是研究对象。本调查的目的是检验药品包装说明书对神经精神科患者依从性的影响。一家神经精神科诊所四分之一的951名患者收到了一份问卷,该问卷调查了收入行为以及对药品包装说明书重要性的估计。352名患者回答了问卷。只有15.6%的患者拒绝回答问卷。其余患者因各种不同原因(痴呆、失语、急性精神障碍、外国血统、行动不便等)无法回答。98.1%的患者认为药品包装说明书很重要。老年患者和教育程度较低的患者认为药品包装说明书内容过于繁杂。只有少数患者(11.5%)让医生解释药品包装说明书。86.3%的患者认为医生开的药是正确的。然而,58.1%的患者对医生提供的信息不满意。神经症患者对医生的解释尤其不满意(77.3%)。73.3%的患者会因药品包装说明书中描述的副作用而偶尔或经常不敢服药。如果医生坚持,59.9%的患者会服药。与药品包装说明书的影响无关,57.5%的患者偶尔或经常忘记服药。癫痫患者和帕金森病患者的依从性最高。总之,调查表明,仅通过药品包装说明书进行解释与医生进行解释相比,会导致更多的不依从情况。