Lozano Andres M, Hutchison William D
Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada.
Mov Disord. 2002;17 Suppl 3:S150-4. doi: 10.1002/mds.10157.
The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important.
苍白球内侧部（GPi）是神经外科手术治疗帕金森病和肌张力障碍的靶点。精确靶向苍白球复合体对于确定手术干预的疗效和避免不良反应至关重要。术中微电极记录可用于描述单个苍白球神经元的活动模式和感受野特性，并识别重要的毗邻结构，包括视束和内囊。由于运动障碍的临床特征可能因苍白球复合体内的位置不同而受到不同影响，术中靶向的进一步优化可能变得很重要。
