Greenman Robert L, Axel Leon, Ferrari Victor A, Lenkinski Robert E
Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA.
J Magn Reson Imaging. 2002 Apr;15(4):467-72. doi: 10.1002/jmri.10081.
To investigate the use of a three-dimensional rapid acquisition with relaxation enhancement (RARE) pulse sequence for direct acquisition of phosphocreatine (PCr) images of the human myocardium.
A short elliptical birdcage radiofrequency (RF) body coil was constructed to produce a uniform flip angle throughout the chest cavity. In vivo images using a spectrally-selective RARE sequence with a spatial resolution of 1.2 cm x 1.2 cm x 2.5 cm (4 cm(3)) were acquired in nine minutes and 40 seconds.
Scans of phantoms demonstrated excellent spectral selectivity. The signal-to-noise ratio in the myocardium ranged from 12.6 in the anterior wall to 5.3 in the mid septum.
This study demonstrates that PCr data can be acquired using a three-dimensional RARE sequence with greater spatial and temporal resolution than spectroscopic techniques.
研究使用三维快速采集弛豫增强（RARE）脉冲序列直接采集人体心肌磷酸肌酸（PCr）图像。
构建一个短椭圆形鸟笼式射频（RF）体线圈，以在整个胸腔内产生均匀的翻转角。使用具有1.2 cm×1.2 cm×2.5 cm（4 cm³）空间分辨率的频谱选择性RARE序列，在9分40秒内采集体内图像。
体模扫描显示出优异的频谱选择性。心肌中的信噪比从前壁的12.6到室间隔中部的5.3不等。
本研究表明，使用三维RARE序列可以采集PCr数据，其空间和时间分辨率比光谱技术更高。
