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[全髋关节置换术中基于“压配”概念的非骨水泥型髋臼固定]

[Cementless socket fixation based on the "press-fit" concept in total hip joint arthroplasty].

作者信息

Morscher E W, Widmer K H, Bereiter H, Elke R, Schenk R

机构信息

Orthopädische Universitätsklinik Basel.

出版信息

Acta Chir Orthop Traumatol Cech. 2002;69(1):8-15.

PMID:11951572
Abstract

PURPOSE OF THE STUDY

The key problem of implant fixation in THR is stress distribution, i.e. load transmission between bone and implant. The closer the load transfer is to the original physiological situation, the easier the adaptation of the periprosthetic bone to the new biomechanical conditions after implantation of the cup and the safer is its longlasting fixation. The aims of the studies were 1) to get information about the physiological load transfer in the normal hip joint, 2) to get information about the load transfer between acetabulum and acetabular sockets and vice versa, 3) to measure the periacetabular pelvic bone deformation as the stimulator of the remodelling process (third stage of osseointegration) in the normal hip joint and in hip joints fitted with different acetabular cups, 4) to study the morphological stages of osseointegration of a non-cemented press-fit cup and to compare the morphological structure of the periacetabular bone with the biomechanical data obtained by the in vitro studies and finally, 5) to compare the clinical and radiological outcome of follow-up studies of the senior author's "Press-Fit cup" with the theoretical hypotheses according to the experimental observations.

MATERIAL AND METHODS

Load transfer between the acetabular bone and the femoral head on one side and press-fit cups has been determined by strain gauge measurements, finite element studies, pressure sensitive Fuji prescale films, CT-osteoabsorptiometry and telemetric measurements. Periacetabular deformation has been measured by Imetric Markers. Osseointegration of the senior author's press-fit cup and, thus, the remodelling process of the bony structures adjacent to the cup have been studied in autopsy specimens of THRs which have been in situ for several years.

RESULTS

Load transfer measurements have shown that the main load in the original acetabulum as well as in the acetabulum fitted with a press-fit cup is transmitted to the periphery, especially to the acetabular cortical rim whereas the subchondral bone is exposed to lower, predominantly meridional (tension) stresses. Direct measurements of the periacetabular deformation under load revealed an increase of the peripheral press-fit with increasing stability of a (oversized) press-fit cup. Both the normal as well as the acetabulum fitted with a non-cemented cup deforms in a postero-medial direction. The histo-morphology of the periacetabular bone of autopsy specimens showed excellent bony in- and ongrowth of a porous titanium coating (SULMESH) and bone formation, especially at the periphery in zone 1 and 3 according to DeLee and Charnley.

CONCLUSION

The studies have shown that the subchondral bone plate of the acetabulum has very little supportive function for non-cemented press-fit cups. For the preparation of the acetabulum it is, therefore, more important to ream the sclerotic subchondral bone until there is a well vascularized, well bleeding bone bed to facilitate osseointegration of a non-cemented acetabular socket than to preserve the subchondral bone plate as is the case in cement fixation. A non-cemented press-fit socket must transmit load predominantly to the cortical bone of the acetabular rim. Therefore, a too far medial positioning of the cup, and therefore loosing contact to the cortical rim, must be avoided under all circumstances. The clinical experience with acetabular revisions and with conversions of hip arthrodeses into a THR (where there is no subchondral bone at all) have shown the superiority of a well vascularized over a sclerotic (even mechanically stronger) bone bed. Furthermore, it has been shown that the additional use of screws for fixation of an acetabular cup is not only unnecessary but can be deleterious and causes complications including osteolysis and aseptic loosening.

摘要

研究目的

全髋关节置换术中植入物固定的关键问题是应力分布,即骨骼与植入物之间的负荷传递。负荷传递越接近原始生理状态,髋臼假体植入后假体周围骨适应新生物力学条件就越容易,其长期固定也就越安全。本研究的目的是:1)获取正常髋关节生理负荷传递的信息;2)获取髋臼与髋臼杯之间负荷传递的信息,反之亦然;3)测量髋臼周围骨盆骨变形,作为正常髋关节及安装不同髋臼杯的髋关节中重塑过程(骨整合的第三阶段)的刺激因素;4)研究非骨水泥压配式髋臼杯的骨整合形态学阶段,并将髋臼周围骨的形态结构与体外研究获得的生物力学数据进行比较;最后,5)根据实验观察结果,将资深作者的“压配式髋臼杯”随访研究的临床和放射学结果与理论假设进行比较。

材料与方法

通过应变片测量、有限元研究、压敏富士预校准薄膜、CT骨吸收测量法和遥测测量法,确定髋臼骨与股骨头一侧以及压配式髋臼杯之间的负荷传递。通过Imetric标记测量髋臼周围变形。在原位数年的全髋关节置换术尸检标本中,研究了资深作者的压配式髋臼杯的骨整合情况,以及因此杯邻近骨结构的重塑过程。

结果

负荷传递测量表明,原始髋臼以及安装压配式髋臼杯的髋臼中的主要负荷传递到周边,尤其是髋臼皮质边缘,而软骨下骨承受较低的、主要是纵向(张力)应力。负荷下髋臼周围变形的直接测量显示,随着(过大尺寸)压配式髋臼杯稳定性的增加,周边压配增加。正常髋臼以及安装非骨水泥杯的髋臼均向后内侧方向变形。尸检标本髋臼周围骨的组织形态学显示,多孔钛涂层(SULMESH)有良好的骨长入和骨形成,尤其是在DeLee和Charnley所定义的1区和3区周边。

结论

研究表明,髋臼软骨下骨板对非骨水泥压配式髋臼杯的支撑功能很小。因此,对于髋臼准备,与骨水泥固定时保留软骨下骨板的情况相比,更重要的是磨削硬化的软骨下骨,直至形成血管丰富、出血良好的骨床,以促进非骨水泥髋臼杯的骨整合。非骨水泥压配式髋臼杯必须将负荷主要传递到髋臼边缘的皮质骨。因此,在任何情况下都必须避免髋臼杯过于向内侧定位,从而失去与皮质边缘的接触。髋臼翻修以及髋关节融合转换为全髋关节置换术(此处根本没有软骨下骨)的临床经验表明,血管丰富的骨床优于硬化(甚至机械强度更高)的骨床。此外,研究表明,额外使用螺钉固定髋臼杯不仅没有必要,而且可能有害,并会导致包括骨溶解和无菌性松动在内的并发症。

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