Motomura Naoyasu, Satani Seiji, Inaba Masaaki
Mental Health Division, Department of Health Science, Osaka Kyoiku University, Kashiwara, Osaka, Japan.
Psychiatry Clin Neurosci. 2002 Apr;56(2):199-202. doi: 10.1046/j.1440-1819.2002.00944.x.
We report the identical monozygotic twin cases of agenesis of the corpus callosum that demonstrated schizophrenic disorder. Patients were 26-year-old twin brothers and both cases were diagnosed as having schizophrenia using DSM-III-R diagnostic criteria. On magnetic resonance imagings both cases demonstrated the total agenesis of the corpus callosum and the anterior commissure was hypertrophic. We speculated that the developmental disturbance of the corpus callosum might be related to the cause of the psychiatric disorders in the present cases.
我们报告了胼胝体发育不全的同卵双胞胎病例，这对双胞胎均患有精神分裂症。患者为一对26岁的双胞胎兄弟，两例均根据《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）诊断标准被诊断为精神分裂症。磁共振成像显示，两例均存在胼胝体完全缺失，且前连合肥大。我们推测，在本病例中，胼胝体的发育障碍可能与精神疾病的病因有关。
